18F-氟脱氧葡萄糖正电子发射断层显像在结外起源淋巴瘤中的表现——3例弥漫性大B细胞型淋巴瘤病例分析

Findings of fluorine-18-FDG PET in extranodal origin lymphoma--in three cases of diffuse large B cell type lymphoma.

作者信息

Nihashi Takashi, Hayasaka Kazumasa, Itou Toshihide, Ito Kengo, Kato Rikio, Okae Toshiharu, Ishigaki Takeo

机构信息

Department of Radiology, National Center for Geriatrics and Gerontology, 36-3, Gengo, Morioka-cho, Ohbu 474-8522, Japan.

出版信息

Ann Nucl Med. 2006 Dec;20(10):689-93. doi: 10.1007/BF02984681.

DOI:10.1007/BF02984681

PMID:17385308

Abstract

F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) is an excellent modality for non-invasive functional imaging of malignant lymphoma and is highly sensitive and specific for the detection of lymphoma lesions. Here, we report the findings of FDG-PET for three cases of diffuse large B cell type lymphoma (DLBCL) with extranodal tumors in the breast, stomach, and liver plus spleen, respectively. The whole body FDG-PET findings showed no evidence of lymph node (LN) involvement or distant metastasis. Strong FDG accumulations were observed in the only extranodal sites by whole body FDG-PET. Therefore, we could confirm that these cases were extranodal primary origins. Whole body PET is useful to determine the primary sites, that is, extranodal origin DLBCL with its clear images.

摘要

F-18氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）是恶性淋巴瘤非侵入性功能成像的优秀方式，对淋巴瘤病灶的检测具有高度敏感性和特异性。在此，我们报告了FDG-PET对三例分别发生于乳腺、胃以及肝脏加脾脏的结外肿瘤的弥漫性大B细胞型淋巴瘤（DLBCL）的检查结果。全身FDG-PET检查结果显示无淋巴结受累或远处转移迹象。全身FDG-PET仅在结外部位观察到强烈的FDG聚集。因此，我们可以确认这些病例为结外原发性起源。全身PET有助于确定原发性部位，即结外起源的DLBCL，其图像清晰。