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甲状腺乳头状癌的颅骨转移

Skull metastasis of thyroid papillary carcinoma.

作者信息

Miyawaki Satoru, Yamazaki Ryuichi, Harada Takehiko, Takanashi Shigehiko, Nagashima Tadashi, Nakaguchi Hiroshi, Okazaki Ryo, Yamazaki Kazuhito, Ishida Yasuo, Matsuno Akira

机构信息

Department of Neurosurgery, Teikyo University Ichihara Hospital, 3426-3 Anesaki, Ichihara City, Chiba 299-0111, Japan.

出版信息

J Clin Neurosci. 2007 May;14(5):481-4. doi: 10.1016/j.jocn.2006.01.032.

Abstract

Skull metastasis of thyroid carcinoma is rare. The majority of skull metastases of thyroid carcinoma are of the follicular subtype, rather than thyroid papillary carcinoma. In this report, a 55-year-old woman with skull metastasis from thyroid papillary carcinoma is presented. The metastatic lesion of the skull was hypervascular and osteolytic, and the bleeding was profuse during resection. There have been only four reports of skull metastasis from thyroid papillary carcinoma. The mean period from the initial diagnosis of thyroid carcinoma until the detection of skull metastasis is 23.3 years, whereas in this patient, it was about 2 years. Therefore, in the clinical course of thyroid papillary carcinoma, skull metastasis should be considered, and the patient should be meticulously followed up.

摘要

甲状腺癌颅骨转移罕见。甲状腺癌颅骨转移大多为滤泡亚型,而非甲状腺乳头状癌。本报告介绍了一名55岁患有甲状腺乳头状癌颅骨转移的女性。颅骨转移病灶血管丰富且呈溶骨性,切除时出血量大。甲状腺乳头状癌颅骨转移仅有4例报告。从甲状腺癌初诊至发现颅骨转移的平均时间为23.3年,而该患者约为2年。因此,在甲状腺乳头状癌的临床病程中,应考虑颅骨转移,并对患者进行细致随访。

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