Senturk H, Cumali R
Department of Gastroenterology, University of Istanbul, Istanbul,Turkey.
Int J Biol Markers. 2007 Jan-Mar;22(1):19-23. doi: 10.5301/jbm.2008.1034.
Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.
报告了3例血清甲胎蛋白极度升高（>10,000 ng/mL）且伴有失代偿性肝硬化但未发现肝细胞癌的病例。2例患者死于肝功能衰竭，1例在肝移植后存活。肝硬化中甲胎蛋白极度升高且与肝细胞癌无关预示着预后不良，需要紧急进行肝移植。
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