Yawe K T, Tahir M B, Nggada H A
Department of Surgery, University of Maiduguri Teaching Hospital, Maiduguri.
West Afr J Med. 2006 Oct-Dec;25(4):298-300.
Prostate cancer is the sixth most important cancer in the world, and its incidence in blacks has been on the increase. It is a very important cause of morbidity and mortality. In North-eastern Nigeria, reports on prostate cancer have been scarce. The aim of this paper is to highlight the clinico-pathological features and management of prostate cancer in north-eastern Nigeria.
The clinical records and histopathological slides of all prostate cancer patients seen at the UMTH from January 1987 to December 2004 were retrospectively reviewed. The total number of cancers diagnosed during this period was also obtained from the cancer registry.
Prostate cancer was seen in 165 patients and accounted for 6.15% of cancers diagnosed in this hospital. Majority of patients (56%) were aged 65 years and below and most presenting symptoms were similar to those of benign prostatic hypertrophy (BPH). The diagnosis was made in most cases on the basis of DRE, USS, PSA, and confirmed by trucut prostatic biopsy. Since most cases were advanced, the most frequent palliative treatment was subcapsular orchidectomy, which was psychologically satisfying to patients. Follow-up was very poor, only 26% at 3 years.
Since most patients present late we conclude that prostate cancer should be suspected in men of 50 years and above who present with symptoms of prostatism and should be investigated promptly. Furthermore, aggressive screening of men in this age group would facilitate early diagnosis.
前列腺癌是全球第六大重要癌症,其在黑人中的发病率一直在上升。它是发病和死亡的一个非常重要的原因。在尼日利亚东北部,关于前列腺癌的报道很少。本文旨在强调尼日利亚东北部前列腺癌的临床病理特征及治疗。
回顾性分析1987年1月至2004年12月在UMTH就诊的所有前列腺癌患者的临床记录和组织病理学切片。这一时期诊断出的癌症总数也从癌症登记处获取。
165例患者被诊断为前列腺癌,占该医院诊断出癌症的6.15%。大多数患者(56%)年龄在65岁及以下,大多数出现的症状与良性前列腺增生(BPH)相似。大多数病例的诊断基于直肠指检(DRE)、超声检查(USS)、前列腺特异性抗原(PSA),并通过前列腺穿刺活检确诊。由于大多数病例已处于晚期,最常见的姑息治疗是包膜下睾丸切除术,这在心理上让患者满意。随访情况很差,3年时只有26%的患者接受了随访。
由于大多数患者就诊时已处于晚期,我们得出结论,对于50岁及以上出现前列腺症状的男性应怀疑患有前列腺癌,并应立即进行检查。此外,对该年龄组男性进行积极筛查将有助于早期诊断。