Bengtson Ann, Karlsson Thomas, Herlitz Johan
Institute of Health and Care Sciences, University of Göteborg, Sweden.
Int J Cardiol. 2008 Jan 24;123(3):271-6. doi: 10.1016/j.ijcard.2006.12.009. Epub 2007 Apr 3.
To describe: a/ the improvement in quality of life (QoL) among patients on the waiting list for coronary revascularisation and b/ the association between QoL and very long-term mortality.
All patients on the waiting list for possible coronary revascularisation in western Sweden during one week in September 1990.
QoL was assessed at the start of the survey and one year later among patients who both were and were not revascularised. Survival data were gathered for the subsequent 14 years.
From the start, 883 patients were evaluated in the survey. Among patients who were revascularised, an improvement was seen in all the aspects of QoL that were studied during the first year as compared with patients who were not revascularised, in whom only minor changes in QoL were seen during the first year. After one year, there were seven aspects of QoL which were significantly associated with the risk of death during the subsequent 14 years, when adjusting for age, sex, previous history and extent of coronary artery disease. They were: tiredness (OR=1.4), weakness (OR=1.5), lack of energy (OR=1.5), inability to react (OR=1.7), use of sedatives (OR=3.2), dyspnea when dressing (OR=2.1) and chest pain when dressing (OR=1.9).
Among patients on the waiting list for possible coronary revascularisation, there was a marked improvement in QoL among those who were revascularised. In a variety of aspects of QoL, an association with the very long-term risk of death was observed.
描述:a/ 冠状动脉血运重建等待名单上患者的生活质量(QoL)改善情况;b/ QoL与极长期死亡率之间的关联。
1990年9月某一周瑞典西部等待可能进行冠状动脉血运重建的所有患者。
在调查开始时以及一年后对接受和未接受血运重建的患者进行QoL评估。收集随后14年的生存数据。
从一开始,883名患者接受了调查评估。与未接受血运重建的患者相比,接受血运重建的患者在第一年所研究的QoL各个方面均有改善,而未接受血运重建的患者在第一年QoL仅有微小变化。一年后,在调整年龄、性别、既往病史和冠状动脉疾病程度后,有七个QoL方面与随后14年的死亡风险显著相关。它们是:疲劳(比值比[OR]=1.4)、虚弱(OR=1.5)、精力不足(OR=1.5)、反应迟钝(OR=1.7)、使用镇静剂(OR=3.2)、穿衣时呼吸困难(OR=2.1)和穿衣时胸痛(OR=1.9)。
在等待可能进行冠状动脉血运重建的患者中,接受血运重建的患者QoL有显著改善。在QoL的多个方面,观察到与极长期死亡风险存在关联。