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参与家族史乳房X线筛查项目的年轻女性中与乳腺癌特异性困扰相关的因素。

Factors associated with breast cancer-specific distress in younger women participating in a family history mammography screening programme.

作者信息

Henderson B J, Tyndel S, Brain K, Clements A, Bankhead C, Austoker J, Watson E, Duffy Stephen, Evans Gareth, Fielder Hilary, Gray Jonathon, Mackay James, Macmillan Douglas

机构信息

Institute of Medical and Social Care Research, Ardudwy, Normal Site, University of Wales, Bangor, Gwynedd LL57 2PX, UK.

出版信息

Psychooncology. 2008 Jan;17(1):74-82. doi: 10.1002/pon.1201.

Abstract

This multi-centre study examined factors associated with breast cancer-specific distress in 2321 women under 50 who are on a mammographic screening programme on account of their family history. Women were recruited from 21 UK centres, and completed a questionnaire one month before their screening appointment. The transactional theory of stress, appraisal, and coping provided the theoretical framework for the study. Factors measured included screening history, family history, perceived risk, cognitive appraisals, coping, optimism, and cancer worry. The findings indicate that the majority of women appraise their family history as being relevant and somewhat threatening to personal well-being, but something they can deal with emotionally. Acceptance was the most commonly used coping strategy. Hierarchical regression analysis identified that the factors most significantly associated with distress were an appraisal of high relevance and threat, increased risk perception, low dispositional optimism, and the use of both avoidant and task-orientated coping strategies. Women with children and those with relatives who have died from breast cancer were also more distressed. To conclude, most women appraised their situation positively but there is a potential profile of risk factors which may help clinicians identify those women who need extra psychological support as they progress through screening.

摘要

这项多中心研究调查了2321名50岁以下因家族病史而参加乳房X光筛查项目的女性中与乳腺癌特异性困扰相关的因素。这些女性来自英国的21个中心,在筛查预约前一个月完成了一份问卷。压力、评估和应对的交互作用理论为该研究提供了理论框架。所测量的因素包括筛查史、家族病史、感知风险、认知评估、应对方式、乐观程度和癌症担忧。研究结果表明,大多数女性认为她们的家族病史与自身相关,且对个人幸福有一定威胁,但她们在情感上能够应对。接受是最常用的应对策略。分层回归分析表明,与困扰最显著相关的因素是对高相关性和威胁的评估、风险感知增加、性格乐观程度低,以及同时使用回避型和任务导向型应对策略。有孩子的女性以及有亲属死于乳腺癌的女性也更易感到困扰。总之,大多数女性对自己的情况评估较为积极,但存在一些潜在的风险因素特征,这可能有助于临床医生识别出那些在筛查过程中需要额外心理支持的女性。

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