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疑似社区获得性肺炎患者影像学表现的临床指标:谁需要进行胸部X光检查?

Clinical indicators of radiographic findings in patients with suspected community-acquired pneumonia: who needs a chest x-ray?

作者信息

O'Brien William T, Rohweder Daniel A, Lattin Grant E, Thornton Jennifer A, Dutton John P, Ebert-Long Deborah L, Duncan Matthew D

机构信息

Department of Diagnostic Radiology, David Grant US Air Force Medical Center, Travis AFB, CA 94535, USA.

出版信息

J Am Coll Radiol. 2006 Sep;3(9):703-6. doi: 10.1016/j.jacr.2006.02.007.

Abstract

PURPOSE

To develop a prediction rule for the use of chest radiographs in evaluating for community-acquired pneumonia (CAP) based on presenting signs and symptoms.

PATIENTS AND METHODS

Adult patients with acute respiratory symptoms and positive chest radiographic results from October 2004 through April 2005 were enrolled as positive cases (n = 350). An equal number of age-matched controls with acute respiratory symptoms but negative radiographic results were included. Data analyses were performed on the 6 most common individual clinical indicators (cough, sputum production, fever, tachycardia, tachypnea, and abnormal physical examination results). Additional analyses were performed for any vital sign abnormality and for the presence of vital sign or physical examination abnormalities.

RESULTS

The data show that vital sign and physical examination findings are useful screening parameters for CAP, demonstrating a sensitivity of 95%, a specificity of 56%, and an odds ratio of 24.9 [corrected] in the presence of vital sign or physical examination abnormalities. In light of these results, the authors developed a prediction rule for low-risk patients with reliable follow-up, which states that chest radiographs are unnecessary in the presence of normal vital signs and physical examination findings.

CONCLUSION

The data suggest that chest radiographs are unnecessary in patients with acute respiratory symptoms who present with normal vital signs and physical examination findings. Because approximately 5% of cases would be missed, however, these criteria are useful only for patients with reliable follow-up and a low likelihood of morbidity if CAP is not detected initially.

摘要

目的

基于呈现出的体征和症状,制定一项用于评估社区获得性肺炎(CAP)时胸部X光片使用的预测规则。

患者与方法

纳入2004年10月至2005年4月期间有急性呼吸道症状且胸部X光片结果呈阳性的成年患者作为阳性病例(n = 350)。纳入同等数量年龄匹配、有急性呼吸道症状但X光片结果为阴性的对照。对6个最常见的个体临床指标(咳嗽、咳痰、发热、心动过速、呼吸急促及体格检查异常结果)进行数据分析。对任何生命体征异常以及生命体征或体格检查异常的存在情况进行了额外分析。

结果

数据表明,生命体征和体格检查结果是CAP有用的筛查参数,在存在生命体征或体格检查异常时,敏感性为95%,特异性为56%,优势比为24.9[校正后]。鉴于这些结果,作者为有可靠随访的低风险患者制定了一项预测规则,该规则指出,在生命体征和体格检查结果正常的情况下,无需进行胸部X光片检查。

结论

数据表明,对于生命体征和体格检查结果正常的急性呼吸道症状患者,无需进行胸部X光片检查。然而,由于约5%的病例会被漏诊,因此这些标准仅对有可靠随访且如果最初未检测出CAP发病可能性较低的患者有用。

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