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激光显微手术在喉癌治疗中的作用。

The role of laser microsurgery in the treatment of laryngeal cancer.

作者信息

Ambrosch Petra

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Germany.

出版信息

Curr Opin Otolaryngol Head Neck Surg. 2007 Apr;15(2):82-8. doi: 10.1097/MOO.0b013e3280147336.

Abstract

PURPOSE OF REVIEW

Transoral laser microsurgery has developed in recent years into a surgical method that combines a minimally invasive approach with the surgical precision of laser and microscope. The outcomes of laser microsurgical treatment of laryngeal carcinomas are reviewed and compared with the results of competitive standard procedures.

RECENT FINDINGS

Laser microsurgery is widely acknowledged to have advantages in the treatment of early glottic carcinoma. In the treatment of glottic carcinoma causing impaired mobility or fixation of the vocal cord the role of laser surgery has not yet been definitively assessed. Based on published results, primary laser therapy can achieve local tumor control with a functional residual larynx in approximately 70-80% of cases. In patients with early or moderately advanced supraglottic carcinoma, laser microsurgery is comparable to open supraglottic laryngectomy in terms of local control and survival. With regard to organ preservation, laser microsurgery is comparable to open supraglottic laryngectomy but superior to radiotherapy. Microsurgery can preserve functionally important structures, allowing for early swallowing rehabilitation while avoiding tracheotomy.

SUMMARY

This review elucidates the role of laser microsurgical partial resections of the larynx in comparison with other treatment modalities.

摘要

综述目的

近年来,经口激光显微手术已发展成为一种将微创方法与激光及显微镜的手术精准性相结合的手术方式。本文对喉癌激光显微手术治疗的结果进行综述,并与其他标准治疗方法的结果进行比较。

最新发现

激光显微手术在早期声门型癌的治疗中具有公认的优势。在治疗导致声带活动受限或固定的声门型癌时,激光手术的作用尚未得到明确评估。根据已发表的结果,原发性激光治疗在约70-80%的病例中可实现局部肿瘤控制并保留功能正常的喉。对于早期或中晚期声门上型癌患者,激光显微手术在局部控制和生存率方面与开放性声门上喉切除术相当。在器官保留方面,激光显微手术与开放性声门上喉切除术相当,但优于放射治疗。显微手术可保留功能重要的结构,实现早期吞咽功能恢复,同时避免气管切开。

总结

本综述阐明了喉激光显微手术部分切除术与其他治疗方式相比的作用。

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