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宫内生长受限新生儿早产后人乳中表皮生长因子浓度降低。

Decreased human milk concentration of epidermal growth factor after preterm delivery of intrauterine growth-restricted newborns.

作者信息

Oslislo Anna, Czuba Zenon, Sławska Helena, Kaźmierczak Wojciech, Król Wojciech

机构信息

Department of Perinatology and Gynecology, Medical University of Silesia, Zabrze, Poland.

出版信息

J Pediatr Gastroenterol Nutr. 2007 Apr;44(4):464-7. doi: 10.1097/MPG.0b013e3180331e15.

Abstract

BACKGROUND AND AIM

The aim of the study was to compare epidermal growth factor (EGF) concentration in 81 colostrum samples collected from mothers of newborns in the following growth categories: preterm appropriate for gestational age (AGA), preterm small for gestational age (SGA), and full term (FT).

RESULTS

Significantly higher concentrations of EGF were found in the colostrum of mothers who delivered premature AGA infants at less than 32 weeks of gestation compared with mothers who delivered premature SGA babies at the same gestational age.

CONCLUSIONS

We concluded that the maternal compensatory mechanism accelerating the development of immature breast-fed infants may be disturbed when gestation is complicated by intrauterine growth retardation.

摘要

背景与目的

本研究旨在比较从以下生长类别新生儿母亲处收集的81份初乳样本中表皮生长因子(EGF)的浓度:早产适于胎龄儿(AGA)、早产小于胎龄儿(SGA)和足月儿(FT)。

结果

与在相同孕周分娩早产SGA婴儿的母亲相比,在妊娠小于32周时分娩早产AGA婴儿的母亲的初乳中发现EGF浓度显著更高。

结论

我们得出结论,当妊娠并发宫内生长迟缓时,加速未成熟母乳喂养婴儿发育的母体代偿机制可能会受到干扰。

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