Maturen Katherine E, Adusumilli Saroja, Blane Caroline E, Arbabi Saman, Williams David M, Fitzgerald James T, Vine Adrian A
Department of Radiology, Stanford University Hospital and Clinics, Stanford, CA 94305-5105, USA.
J Trauma. 2007 Mar;62(3):740-5. doi: 10.1097/01.ta.0000235508.11442.a8.
To assess the ability of contrast enhanced computed tomography (CECT) to detect active hemorrhage and other vascular injuries in chest, abdominal, and pelvic trauma patients, using angiographic findings and need for intervention as paired gold standards.
We obtained approval from the Institutional review board for a retrospective search of the radiology information system: seeking trauma patients undergoing angiography within 24 hours of CECT for chest, abdominal, or pelvic injuries. CECT protocol was standard trauma CT, not specialized for CT angiography. Angiographic techniques varied with indication. Clinical and imaging reports and selected radiologic studies were reviewed, but the original dictated report was the interpretive standard. We used Fisher's exact test for statistical analysis.
During the 30-month study period, 466 patients underwent emergent interventional radiologic procedures. Of those, 418 were excluded for nontrauma indications or neuroangiographic procedures. Fourty-eight patients (33 male, 15 female, average age 43.4) thus constituted the study population in whom we evaluated 63 traumatic injuries. CT findings had statistically significant associations (p < 0.0001) with both angiographic evidence of active hemorrhage and the need for intervention, which were tabulated separately. CT had 94.1% sensitivity and 97.6% negative predictive value (NPV) for detection of active hemorrhage, and 92.6% sensitivity and 91.2% NPV for predicting need for surgical or endovascular intervention.
CECT findings correlate strongly with angiographic findings, though sensitivity remains imperfect. However, when CT is used in the context of other clinical features, particularly hemodynamic instability, it may enable clinicians to reserve emergent angiography for those patients in whom emergent intervention is planned.
以血管造影结果和干预需求作为配对金标准,评估对比增强计算机断层扫描(CECT)检测胸部、腹部和盆腔创伤患者活动性出血及其他血管损伤的能力。
我们获得了机构审查委员会的批准,对放射学信息系统进行回顾性检索:寻找在胸部、腹部或盆腔损伤的CECT检查后24小时内接受血管造影的创伤患者。CECT方案为标准创伤CT,并非专门用于CT血管造影。血管造影技术因适应证而异。回顾了临床和影像报告以及选定的放射学研究,但原始口述报告为解释标准。我们使用Fisher精确检验进行统计分析。
在30个月的研究期间,466例患者接受了紧急介入放射学检查。其中,418例因非创伤适应证或神经血管造影检查而被排除。48例患者(33例男性,15例女性,平均年龄43.4岁)构成了研究人群,我们在其中评估了63处创伤性损伤。CT表现与活动性出血的血管造影证据以及干预需求均具有统计学显著相关性(p < 0.0001),分别进行了列表统计。CT检测活动性出血的敏感性为94.1%,阴性预测值(NPV)为97.6%;预测手术或血管内介入需求的敏感性为92.6%,NPV为91.2%。
CECT表现与血管造影结果密切相关,尽管敏感性仍不完美。然而,当CT结合其他临床特征,特别是血流动力学不稳定时,它可能使临床医生能够为计划进行紧急干预的患者保留紧急血管造影检查。