损伤的代谢反应及合成代谢激素的作用。
Metabolic response to injury and role of anabolic hormones.
作者信息
Wanek Sandra, Wolf Steven E
机构信息
Burn Center, US Army Institute of Surgical Research, 3400 Rawley E. Chambers Avenue, Fort Sam Houston, TX 78234, USA.
出版信息
Curr Opin Clin Nutr Metab Care. 2007 May;10(3):272-7. doi: 10.1097/MCO.0b013e3280f31b17.
PURPOSE OF REVIEW
To provide a short review of the literature describing the hypermetabolic response to injury and potential treatments. Associated findings include changes in inflammatory mediators and secreted hormones.
RECENT FINDINGS
Treatments should be aimed at decreasing the response and potentially the use of anabolic agents. Of note, recent interest in the hyperglycemic response to injury and insulin treatment will be highlighted.
SUMMARY
The current metabolic care of the burned patient including nutrition is now being unfolded. It is relatively clear that anabolic treatment should be considered in all those with severe injury. Timing of the treatment, however, is still a topic of discussion.
综述目的
简要回顾描述损伤后高代谢反应及潜在治疗方法的文献。相关发现包括炎症介质和分泌激素的变化。
最新发现
治疗应旨在减轻反应并可能使用合成代谢药物。值得注意的是，将重点介绍近期对损伤后高血糖反应及胰岛素治疗的关注。
总结
目前包括营养在内的烧伤患者代谢护理正在展开。相对明确的是，所有严重损伤患者都应考虑进行合成代谢治疗。然而，治疗时机仍是一个讨论话题。
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