Monitoring death and cancer in children born to HIV-infected women in England and Wales: use of HIV surveillance and national routine data.

There may be long-term adverse health effects of in-utero antiretroviral therapy exposure. Data on children reported through national HIV surveillance were linked to routinely collected cancer and death data: a process known as "flagging". Ninety-five per cent (2612) of reported children born in 2001-2004 in England or Wales who were uninfected or of indeterminate infection status were flagged. By the end of 2005, no cancers and 14 deaths (three uninfected and 11 indeterminate) had been notified.