Cambal M, Labas P, Kozanek M, Takac P, Krumpalova Z
1st Department of Surgery, University Hospital, and Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Bratisl Lek Listy. 2006;107(11-12):442-4.
To establish a maggot debridement therapy unit and assess efficacy of this method in chronic conservative non-treatable leg ulcers in patient in whom conventional therapy failed.
From August 2004 to December 2005 we treated with Maggot debridement therapy (MDT) 10 patients, 6 men and 4 women, with 13 leg ulcers treated first with conventional and then with maggot therapy. Average age of these patients was 55 years, 11 wounds were of venous and 2 of arterial origin. 7 patients had diabetes mellitus.
1 patient with arterial ulcers underwent supracondylar amputation, 2 patients were re-admitted for recurrent ulcers, one extremely obese patient with cardiovascular co-morbidity did not heal, but all other ulcers have been healed, cleared or minimised during 4-8 week MDT. We observed massive growth of granulation tissue and microbiological cleaning of these wounds. No adverse effects were observed.
Maggot therapy was more effective and efficient in debriding non-healing leg ulcers than a conservative treatment (Fig. 3, Ref. 6).
建立一个蛆虫清创治疗单元,并评估该方法对传统治疗无效的慢性保守治疗不可治愈的腿部溃疡患者的疗效。
2004年8月至2005年12月,我们对10例患者(6例男性,4例女性)的13处腿部溃疡进行了蛆虫清创治疗(MDT),这些溃疡先接受了传统治疗,然后采用蛆虫疗法。这些患者的平均年龄为55岁,11处伤口源于静脉,2处源于动脉。7例患者患有糖尿病。
1例动脉溃疡患者接受了髁上截肢术,2例患者因复发性溃疡再次入院,1例患有心血管合并症的极度肥胖患者未愈合,但在4至8周的蛆虫清创治疗期间,所有其他溃疡均已愈合、清除或缩小。我们观察到这些伤口的肉芽组织大量生长且微生物得到清除。未观察到不良反应。
与保守治疗相比,蛆虫疗法在清创不愈合的腿部溃疡方面更有效且高效(图3,参考文献6)。