来自尖叶蕉变种“Yangambi km 5”（AAA）的菲那烯酮类化合物及其对香蕉黑条叶斑病菌的活性。

Phenalenone-type compounds from Musa acuminata var. "Yangambi km 5" (AAA) and their activity against Mycosphaerella fijiensis.

作者信息

Otálvaro Felipe, Nanclares Juliana, Vásquez Luz Estella, Quiñones Winston, Echeverri Fernando, Arango Rafael, Schneider Bernd

机构信息

Departamento de Ingeniería, Universidad Nacional de Colombia sede Palmira, Carrera 32 Chapinero vía Candelaria, A.A 237, Palmira-Valle del Cauca, Colombia.

出版信息

J Nat Prod. 2007 May;70(5):887-90. doi: 10.1021/np070091e. Epub 2007 Apr 12.

DOI:10.1021/np070091e

PMID:17428093

Abstract

Two perinaphthenone-type compounds (1 and 2) were isolated together with four known phenylphenalenones (3-6) from the rhizomes of Musa acuminata var. "Yangambi km 5". The structures of the new phenalenones were assigned as 2-hydroxy-1H-phenalen-1-one (1) and 2-methoxy-1H-phenalen-1-one (2) on the basis of their spectroscopic data and were confirmed by synthesis. Compounds 1 and 2 displayed significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylphenalenones.

摘要

从尖叶蕉变种“Yangambi km 5”的根茎中分离出两种苊醌型化合物（1和2）以及四种已知的苯并菲酮类化合物（3 - 6）。基于光谱数据，新的苯并菲酮类化合物的结构被确定为2 - 羟基 - 1H - 苯并菲 - 1 - 酮（1）和2 - 甲氧基 - 1H - 苯并菲 - 1 - 酮（2），并通过合成得到证实。与其他苯并菲酮类化合物相比，化合物1和2对香蕉黑条叶斑病菌显示出显著增强的活性。