Crawford Fred A
Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2007:11-20. doi: 10.1053/j.pcsu.2007.01.017.
Complete atrioventricular septal defects have been repaired at the Medical University of South Carolina for the past 25 years using the "single-patch technique" as first described by the Mayo Clinic group in 1968. In this technique, the single atrioventricular valve is separated into left (mitral) and right (tricuspid) components by dividing the superior and inferior bridging leaflets back to the annulus. A single patch of bovine pericardium is sutured to the right ventricular aspect of the ventricular septum, the previously divided valve leaflets are resuspended to the patch, the "cleft" in the left-sided valve is closed with interrupted sutures, and the atrial component of the defect closed by suturing the patch to the atrial septum with a continuous suture. Since 1995, there have been no operative deaths in the 88 consecutive infants undergoing this repair in our institution. Nine patients (10.2%) have required reoperation for severe mitral regurgitation. While the issue of operative mortality in patients undergoing single-patch repair of complete atrioventricular septal defect has largely been eliminated, residual or recurrent mitral regurgitation continues to be a problem.
在过去25年里,南卡罗来纳医科大学一直采用1968年梅奥诊所团队首次描述的“单补片技术”来修复完全性房室间隔缺损。在该技术中,通过将上、下桥瓣叶向瓣环方向分开,将单一的房室瓣分为左(二尖瓣)、右(三尖瓣)两部分。将一片牛心包补片缝合至室间隔的右心室面,将先前分开的瓣叶重新悬吊于补片上,用间断缝合关闭左侧瓣膜的“裂缺”,通过连续缝合将补片与房间隔缝合以关闭缺损的心房部分。自1995年以来,在我们机构连续接受该修复手术的88例婴儿中无手术死亡病例。9例患者(10.2%)因严重二尖瓣反流需要再次手术。虽然完全性房室间隔缺损单补片修复患者的手术死亡率问题在很大程度上已得到解决,但残余或复发性二尖瓣反流仍然是一个问题。