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原发性纤毛运动障碍患者常见变异型免疫缺陷的诊断

Diagnosis of common variable immunodeficiency in a patient with primary ciliary dyskinesia.

作者信息

Skorpinski Edward W, Kung Shiang-Ju, Yousef Ejaz, McGeady Stephen J

机构信息

Berkshire Allergy & Asthma Center, Wyomissing, Pennsylvania 19610, USA.

出版信息

Pediatrics. 2007 May;119(5):e1203-5. doi: 10.1542/peds.2006-2396. Epub 2007 Apr 16.

Abstract

In this case report we describe the first account in the literature of a patient with primary ciliary dyskinesia and common variable immunodeficiency. A 17-year-old boy with previously diagnosed Kartagener syndrome and stable lung disease developed a deteriorating clinical course that prompted the search for a secondary diagnosis. Although both of these rare conditions can result in similar lung pathology, they require different management strategies, which illustrates the need to consider associated diagnoses in complicated clinical situations.

摘要

在本病例报告中,我们描述了文献中首例患有原发性纤毛运动障碍和常见可变免疫缺陷的患者。一名先前被诊断为卡塔格内综合征且肺部疾病稳定的17岁男孩,其临床病程恶化,促使我们寻找继发性诊断。尽管这两种罕见疾病都可能导致相似的肺部病理改变,但它们需要不同的管理策略,这说明了在复杂临床情况下考虑相关诊断的必要性。

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