MacAllister W S, Boyd J R, Holland N J, Milazzo M C, Krupp L B
National Pediatric MS Center at Stony Brook, NY, USA.
Neurology. 2007 Apr 17;68(16 Suppl 2):S66-9. doi: 10.1212/01.wnl.0000259420.54635.63.
Although psychological distress and cognitive dysfunction are well documented in adults with multiple sclerosis (MS), they are poorly understood in children with the disease. Psychosocial difficulty experienced by children and adolescents with MS involves factors common to all chronic illnesses in children, as well as MS-specific factors. The psychosocial manifestations of the disease may affect the patient's self-image, role functioning, mood, and cognition to adversely affect schooling, interpersonal relationships, and treatment compliance. Furthermore, the impact of having a family member with MS may affect overall family functioning. Assessment and interventions for psychosocial and cognitive problems in pediatric MS should be multidisciplinary in nature and address the child's functioning at home, school, and among peers, as well as the effect on the family.
尽管心理困扰和认知功能障碍在成年多发性硬化症（MS）患者中已有充分记载，但在患有该疾病的儿童中却鲜为人知。患有MS的儿童和青少年所经历的心理社会困难涉及儿童所有慢性疾病共有的因素，以及MS特有的因素。该疾病的心理社会表现可能会影响患者的自我形象、角色功能、情绪和认知，从而对学业、人际关系和治疗依从性产生不利影响。此外，家庭成员患有MS的影响可能会波及整个家庭功能。儿科MS患者心理社会和认知问题的评估与干预本质上应是多学科的，要涵盖儿童在家、学校和同伴中的功能状况，以及对家庭的影响。
