Kikuchi Kiyoshi, Ohkusa Yasushi, Sugawara Tamie, Taniguchi Kiyosu, Okabe Nobuhiko
Department of Pediatrics, Shimane Prefectual Central Hospital.
Kansenshogaku Zasshi. 2007 Mar;81(2):162-72. doi: 10.11150/kansenshogakuzasshi1970.81.162.
To detect nosocomial outbreaks early we construct syndromic surveillance for inpatients with fever, respiratory symptoms, diarrhea, vomiting, or rash and evaluate it statistically.
In hospital using electronic medical records since August 1999, we studied the number of inpatients with a certain symptoms from 1999 to 2005. To prospectively detect outbreaks after January 1, 2005, we first estimated the baseline using data from August 1, 1999 to the day before any given day. We then predicted the number of patients on the day and judge whether an outbreak has occurred, evaluating this by checking it sensitivity and specificity to detect outbreaks other than those with previous patterns.
From August 1999 to December 2005, 115,532 patients had fever, 126,443 respiratory symptoms, 87,923 diarrhea, 32,858 vomiting, and 11,212 In 2005, in prospective detection, 23,617 had fever, 23,698 respiratory symptoms, 14,671 diarrhea, 5,893 vomiting, and 2,486 rash.
This hospital had a nosocomial Noro virus outbreak on January 27, 2005. Syndromic surveillance identified an outbreak of vomiting at a 0.1% criterion. Our system thus detects nosocomial outbreaks and is of practical use. The next step will be ward-by-ward examination, after which we will experiment with rapid information collection, analysis, reports of results, and investigation by infection control teams.
为了早期发现医院感染暴发,我们构建了针对发热、呼吸道症状、腹泻、呕吐或皮疹住院患者的症状监测体系,并对其进行统计学评估。
自1999年8月起在一家使用电子病历的医院,我们研究了1999年至2005年有特定症状的住院患者数量。为了前瞻性地检测2005年1月1日之后的暴发,我们首先使用1999年8月1日至任何给定日期前一天的数据估计基线。然后我们预测当天的患者数量并判断是否发生了暴发,通过检查其检测不同于以往模式的暴发的敏感性和特异性来评估。
从1999年8月到2005年12月,115532名患者有发热症状,126443名有呼吸道症状,87923名有腹泻,32858名有呕吐,11212名有皮疹。2005年,在前瞻性检测中,23617名有发热,23698名有呼吸道症状,14671名有腹泻,5893名有呕吐,2486名有皮疹。
该医院在2005年1月27日发生了一次医院诺如病毒暴发。症状监测在0.1%的标准下识别出了一次呕吐暴发。因此,我们的系统能够检测医院感染暴发且具有实际用途。下一步将逐个病房进行检查,之后我们将试验快速信息收集、分析、结果报告以及感染控制团队的调查。