Dersh Jeffrey, Mayer Tom, Theodore Brian R, Polatin Peter, Gatchel Robert J
PRIDE Research Foundation, Dallas, TX, USA.
Spine (Phila Pa 1976). 2007 Apr 20;32(9):1045-51. doi: 10.1097/01.brs.0000261027.28779.52.
An epidemiologic prevalence study.
To clarify the temporal association between work-related injury claims and psychiatric disorders in patients with chronic disabling occupational spinal disorders (CDOSDs).
Few empirical data are available regarding the "chicken-or-egg" question of which occurs first: the injury or incident culminating in the painful CDOSD or the psychiatric disturbance.
Subjects attended a tertiary interdisciplinary rehabilitation program. Psychiatric disorders were assessed using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders (SCID-DSM-IV). Psychiatric disorders were characterized as preexisting if they manifested themselves before the work-related injury claim (whether or not they resolved, continued, or reoccurred after injury). They were determined postinjury diagnoses only if they manifested for the first time after the injury claim.
A total of 38.7% of the present cohort had at least one preexisting major psychiatric disorder, while 98.9% developed one or more psychiatric disorders for the first time after injury onset (57.9% when pain disorder was excluded). The percentage of patients with preexisting psychiatric disorders was lower than general population base rates (48%). The first onset of certain psychiatric disorders was found to be elevated in patients only after the work-related injury; these included Pain Disorder (95.7%), Major Depressive Disorder (49.7%), and Opioid Dependence (15%). Moreover, 5 times as many patients with MDD, and 10 times as many with opioid dependence, developed these disorders for the first time after the injury.
In general, psychiatric disturbance is not a risk factor for developing a CDOSD. Psychiatric disorders are much more likely to develop after the onset of the work injury, indicating that such injuries and accompanying stressors are likely to be precipitants, rather than consequences, of psychopathology.
一项流行病学患病率研究。
阐明慢性致残性职业性脊柱疾病(CDOSD)患者中与工作相关的工伤索赔和精神障碍之间的时间关联。
关于“先有鸡还是先有蛋”的问题,即究竟是导致疼痛性CDOSD的损伤或事件先出现,还是精神障碍先出现,目前几乎没有实证数据。
研究对象参加了三级跨学科康复项目。使用《精神障碍诊断与统计手册》(SCID-DSM-IV)的结构化临床访谈对精神障碍进行评估。如果精神障碍在与工作相关的工伤索赔之前就已出现(无论在受伤后是否缓解、持续或复发),则被归类为既往存在的精神障碍。只有在工伤索赔之后首次出现的精神障碍才被确定为伤后诊断。
本队列中共有38.7%的患者至少有一种既往存在的主要精神障碍,而98.9%的患者在受伤后首次出现一种或多种精神障碍(排除疼痛障碍时为57.9%)。既往存在精神障碍的患者百分比低于一般人群的基线率(48%)。仅在与工作相关的工伤之后,某些精神障碍在患者中的首次发病率升高;这些障碍包括疼痛障碍(95.7%)、重度抑郁症(49.7%)和阿片类药物依赖(15%)。此外,患重度抑郁症的患者中,伤后首次出现该疾病的人数是之前的5倍,患阿片类药物依赖的患者中,这一数字是之前的10倍。
总体而言,精神障碍不是发生CDOSD的危险因素。精神障碍更有可能在工伤发生后出现,这表明此类损伤及伴随的应激源可能是精神病理学的诱发因素,而非结果。