Peifer Kevin J, Shiels Aaron J, Azar Riad, Rivera Ramon E, Eagon J Chris, Jonnalagadda Sreenivasa
Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Gastrointest Endosc. 2007 Aug;66(2):248-52. doi: 10.1016/j.gie.2006.10.012. Epub 2007 Apr 23.
Roux-en-Y gastric bypass is the most frequently performed bariatric surgery for morbid obesity. Gastrojejunal anastomotic strictures are a relatively frequent postoperative complication.
To evaluate the clinical outcomes and therapeutic response to through-the-scope balloon dilation performed to treat anastomotic strictures after Roux-en-Y gastric bypass surgery.
Single-center, retrospective study.
Academic medical center.
Between 1997 and 2005, 801 patients with morbid obesity underwent Roux-en-Y gastric bypass surgery at our institution.
The development of an anastomotic stricture after Roux-en-Y gastric bypass surgery. The response to through-the-scope balloon dilation after diagnosis.
Forty-three of 801 patients (5.4%) developed an anastomotic stricture (26 of 294 open surgeries [8.8%]; 17 of 507 laparoscopic surgeries [3.4%]; P < .001). Strictures were dilated to 15.5 +/- 0.4 mm. There were no perforations or clinically significant bleeding after dilation; 93% of the strictures were successfully managed with 1 or 2 endoscopic sessions. Dilation to at least 15 mm did not affect weight loss at 1 year when compared with the group without a stricture (percentage excess weight loss: stricture group, 76%; no stricture group, 74%).
Single-center, retrospective study.
Endoscopic balloon dilation is a safe and effective method for the management of gastrojejunostomy strictures after Roux-en-Y gastric bypass. Dilation to at least 15 mm is safe and decreases the need for further endoscopic dilation.
Roux-en-Y胃旁路术是治疗病态肥胖最常施行的减肥手术。胃空肠吻合口狭窄是一种相对常见的术后并发症。
评估经内镜球囊扩张治疗Roux-en-Y胃旁路术后吻合口狭窄的临床疗效及治疗反应。
单中心回顾性研究。
学术医学中心。
1997年至2005年间,801例病态肥胖患者在本机构接受了Roux-en-Y胃旁路手术。
Roux-en-Y胃旁路术后吻合口狭窄的发生情况。诊断后经内镜球囊扩张的反应。
801例患者中有43例(5.4%)发生吻合口狭窄(294例开放手术中有26例[8.8%];507例腹腔镜手术中有17例[3.4%];P<0.001)。狭窄部位扩张至15.5±0.4mm。扩张后无穿孔或具有临床意义的出血;93%的狭窄通过1或2次内镜治疗成功处理。与无狭窄组相比,扩张至至少15mm对1年时的体重减轻无影响(超重减轻百分比:狭窄组为76%;无狭窄组为74%)。
单中心回顾性研究。
内镜球囊扩张是治疗Roux-en-Y胃旁路术后胃空肠吻合口狭窄的一种安全有效的方法。扩张至至少15mm是安全可行的,并减少了进一步内镜扩张的必要性。