Vásquez T Patricia, Chanqueo C Leonardo, García C Patricia, Poggi M Helena, Ferrés G Marcela, Bustos M Marisol, Piottante B Antonio
Unidad de Infectología, Servicio de Medicina Interna, Hospital San Juan de Dios, and Laboratorio de Microbiología y Biología Molecular, Pontificia Universidad Católica de Chile.
Rev Chilena Infectol. 2007 Apr;24(2):155-9. doi: 10.4067/s0716-10182007000200012. Epub 2007 Apr 12.
We report the first case of bacillary angiomatosis due to Bartonella quintana affecting a Chilean a HIV positive patient in Chile. He was a 27 years old, heterosexual male, indigent man known to be HIV positive serological status known from September, 2003, under irregular medical control. On April, 2005, he presented a progressive abscess in the frontal region and erythematous papules in the extremities, that extended to face, thorax and mucoses, becoming nodular and violaceous lesions. Bacillary angiomatosis diagnosis was initially sustained on account of the clinical manifestations, and was confirmed by serology and Warthin Starry staining from a skin biopsy. The etiological agent was identified as Bartonella quintana through universal RPC performed from a cutaneous nodule to detect 16S rRNA gen. Azithromycin plus ciprofloxacin was started, besides of anti retroviral therapy antiretroviral, with the lesions being progressively disappearing.
我们报告了智利首例由五日热巴尔通体引起的杆菌性血管瘤病,患者为一名智利HIV阳性患者。他是一名27岁的异性恋男性,贫困,自2003年9月起已知血清学HIV阳性,医疗控制不规律。2005年4月,他额部出现进行性脓肿,四肢出现红斑丘疹,并蔓延至面部、胸部和黏膜,形成结节状和紫红色病变。杆菌性血管瘤病的诊断最初基于临床表现,经血清学检查及皮肤活检的Warthin Starry染色得以确诊。通过对皮肤结节进行通用RPC检测16S rRNA基因,将病原体鉴定为五日热巴尔通体。除抗逆转录病毒治疗外,开始使用阿奇霉素加环丙沙星治疗,病变逐渐消失。