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抑郁的大龄青少年和青年成年人自杀行为的诱因:酒精使用障碍会产生影响吗?

Triggers for suicidal behavior in depressed older adolescents and young adults: do alcohol use disorders make a difference?

作者信息

Sher Leo, Sperling Dahlia, Stanley Barbara H, Carballo Juan J, Shoval Gal, Zalsman Gil, Burke Ainsley K, Mann J John, Oquendo Maria A

机构信息

Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA.

出版信息

Int J Adolesc Med Health. 2007 Jan-Mar;19(1):91-8. doi: 10.1515/ijamh.2007.19.1.91.

Abstract

UNLABELLED

Adolescent suicide is a major social and medical problem. Alcohol use disorders with comorbid major depression represent an especially high-risk profile for suicidal behavior, repeated suicidal behavior and completed suicide. We compared demographic and clinical characteristics, prevalence of interpersonal triggers and the number of triggers for suicidal behavior in depressed late adolescents and young adults with or without comorbid alcohol use disorders.

METHODS

18-26-year-old subjects were recruited through advertising and referrals and participated in mood disorders research in a university hospital. Thirty-eight depressed suicide attempters without a history of any alcohol or substance abuse/dependence and 29 depressed suicide attempters with comorbid alcohol abuse or dependence participated in the study. Demographic and clinical parameters including parameters related to suicidal behavior were examined and recorded.

RESULTS

There was no difference with regard to demographic parameters between the two groups. Depressed suicide attempters with comorbid alcohol use disorders had higher aggression and impulsivity scale scores and were more likely to be tobacco smokers compared to their counterparts without alcohol use disorders. Additionally, there was a trend towards higher lethality of suicide attempts in subjects with alcohol use disorders compared to the other group. We found no difference in the prevalence of interpersonal triggers or in the number of triggers for suicidal behavior between the two groups.

CONCLUSION

It appears that among 18-26-year-old depressed suicide attempters, individuals with comorbid alcohol use disorders are more impaired with regard to aggressiveness and impulsivity compared to persons without comorbid alcohol abuse/dependence.

摘要

未标注

青少年自杀是一个重大的社会和医学问题。伴有重度抑郁症的酒精使用障碍是自杀行为、反复自杀行为和自杀身亡的特别高危因素。我们比较了患有或未患有酒精使用障碍的抑郁晚期青少年和青年成年人的人口统计学和临床特征、人际触发因素的患病率以及自杀行为的触发因素数量。

方法

通过广告和转诊招募18 - 26岁的受试者,他们在一家大学医院参与情绪障碍研究。38名无任何酒精或物质滥用/依赖史的抑郁自杀未遂者和29名伴有酒精滥用或依赖的抑郁自杀未遂者参与了该研究。检查并记录了包括与自杀行为相关参数在内的人口统计学和临床参数。

结果

两组在人口统计学参数方面没有差异。与无酒精使用障碍的抑郁自杀未遂者相比,伴有酒精使用障碍的抑郁自杀未遂者具有更高的攻击性和冲动性量表得分,且更有可能吸烟。此外,与另一组相比,患有酒精使用障碍的受试者自杀未遂的致死率有升高趋势。我们发现两组在人际触发因素的患病率或自杀行为的触发因素数量上没有差异。

结论

在18 - 26岁的抑郁自杀未遂者中,与无酒精滥用/依赖的人相比,伴有酒精使用障碍的个体在攻击性和冲动性方面似乎受损更严重。

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