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一名因隐球菌性脑膜炎导致脑积水的患者在进行脑室腹腔分流术后出现腹部囊肿形成。病例报告:通过手术切除囊肿并使用一种新研发的抗真菌药物(氟康唑)治疗后完全治愈。

Abdominal cyst formation following ventriculoperitoneal shunt in a case of hydrocephalus due to cryptococcal meningitis. Case report: completely cured by surgical removal of the cyst and treatment with a newly developed anti-fungal drug (Difulcan).

作者信息

Izumoto S, Nakagawa H, Fujita T, Kubo S

机构信息

Department of Neurosurgery, Center for Adult Diseases, Osaka, Japan.

出版信息

Surg Neurol. 1991 Nov;36(5):394-9. doi: 10.1016/0090-3019(91)90031-4.

Abstract

A 54-year-old woman was admitted to the hospital for evaluation of meningitis. Tuberculous meningitis was suspected initially because of general findings and a high adenosine deaminase activity (ADA) value in the cerebrospinal fluid. Administration of antituberculous drugs was not effective. Computed tomography scanning revealed progression of ventricular enlargement. A ventriculo-peritoneal shunt was placed upon diagnosis of hydrocephalus due to meningitis. The presence of a large abdominal cyst formation was demonstrated. Cryptococcus was detected in the cyst fluid, leading to a diagnosis of cryptococcal meningitis. Intravenous administration of fluconazole (400 mg/day) was begun. Excision of the cyst was performed when Cryptococcus was no longer detected in the cyst fluid. The patient recovered uneventfully.

摘要

一名54岁女性因脑膜炎评估入院。最初因一般检查结果及脑脊液中腺苷脱氨酶(ADA)活性高而怀疑为结核性脑膜炎。抗结核药物治疗无效。计算机断层扫描显示脑室扩大进展。因脑膜炎诊断为脑积水后行脑室-腹腔分流术。发现有一个大的腹部囊肿形成。在囊液中检测到隐球菌,从而诊断为隐球菌性脑膜炎。开始静脉注射氟康唑(400毫克/天)。当囊液中不再检测到隐球菌时,进行了囊肿切除术。患者顺利康复。

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