Izumoto S, Nakagawa H, Fujita T, Kubo S
Department of Neurosurgery, Center for Adult Diseases, Osaka, Japan.
Surg Neurol. 1991 Nov;36(5):394-9. doi: 10.1016/0090-3019(91)90031-4.
A 54-year-old woman was admitted to the hospital for evaluation of meningitis. Tuberculous meningitis was suspected initially because of general findings and a high adenosine deaminase activity (ADA) value in the cerebrospinal fluid. Administration of antituberculous drugs was not effective. Computed tomography scanning revealed progression of ventricular enlargement. A ventriculo-peritoneal shunt was placed upon diagnosis of hydrocephalus due to meningitis. The presence of a large abdominal cyst formation was demonstrated. Cryptococcus was detected in the cyst fluid, leading to a diagnosis of cryptococcal meningitis. Intravenous administration of fluconazole (400 mg/day) was begun. Excision of the cyst was performed when Cryptococcus was no longer detected in the cyst fluid. The patient recovered uneventfully.
一名54岁女性因脑膜炎评估入院。最初因一般检查结果及脑脊液中腺苷脱氨酶(ADA)活性高而怀疑为结核性脑膜炎。抗结核药物治疗无效。计算机断层扫描显示脑室扩大进展。因脑膜炎诊断为脑积水后行脑室-腹腔分流术。发现有一个大的腹部囊肿形成。在囊液中检测到隐球菌,从而诊断为隐球菌性脑膜炎。开始静脉注射氟康唑(400毫克/天)。当囊液中不再检测到隐球菌时,进行了囊肿切除术。患者顺利康复。