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寻则得之:以副肿瘤性小脑变性为表现的霍奇金淋巴瘤。

Seek and ye shall find: Hodgkin's lymphoma presenting as paraneoplastic cerebellar degeneration.

作者信息

Tie Jeanne, Forgeson Garry, McNabb Andrew, Roebert Justin

机构信息

Midcentral Regional Cancer Treatment Service, Palmerston North.

出版信息

N Z Med J. 2007 Apr 13;120(1252):U2495.

Abstract

Paraneoplastic neurological syndromes (PNS) are rare complications of cancer and may be the presenting sign of an occult malignancy. Diagnosis of PNS is often challenging and treatment of the underlying tumour remains the best therapeutic option for preventing further neurological damage. We report on a patient who developed a rapidly progressive cerebellar ataxia and underwent extensive investigations before a paraneoplastic aetiology was confirmed by detection of an underlying malignancy.

摘要

副肿瘤性神经系统综合征(PNS)是癌症罕见的并发症,可能是隐匿性恶性肿瘤的首发症状。PNS的诊断往往具有挑战性,治疗潜在肿瘤仍然是预防进一步神经损伤的最佳治疗选择。我们报告了一名患者,该患者出现快速进展的小脑共济失调,并在通过检测到潜在恶性肿瘤确诊副肿瘤病因之前接受了广泛的检查。

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