Wilson J F, Freeman S B, Breene D P
Department of Otolaryngology-Head and Neck Surgery, Naval Hospital, Portsmouth, VA 23708-5100.
Arch Otolaryngol Head Neck Surg. 1991 Nov;117(11):1304-6. doi: 10.1001/archotol.1991.01870230120021.
Anterior ischemic optic neuropathy is an uncommon and devastating event that can result in unilateral or bilateral blindness. It has been reported as a complication of ophthalmologic or general surgical and cardiothoracic procedures as well as a spontaneous event in severe systemic disease. Aggravating intraoperative factors include anemia, hemorrhage, hypotension, preexisting small-vessel disease, and increased intraocular pressure. We present a case of anterior ischemic optic neuropathy as a complication in a 48-year-old man undergoing extensive resection of recurrent carcinoma of the head and neck. Possible contributing risk factors in our patient include preexisting hypertension, intraoperative blood loss, previous radical neck dissection with venous compromise, intraoperative head and neck edema, and the use of tightly adherent plastic bubble-type intraoperative eye protection. The possible pathogenesis of this devastating complication and recommendations for prevention and management of anterior ischemic optic neuropathy are described.
前部缺血性视神经病变是一种罕见且具有破坏性的疾病,可导致单眼或双眼失明。它已被报道为眼科手术、普通外科手术、心胸外科手术的并发症,以及严重全身性疾病中的自发事件。术中加重因素包括贫血、出血、低血压、既往存在的小血管疾病和眼压升高。我们报告一例前部缺血性视神经病变,该病变是一名48岁接受广泛切除复发性头颈癌手术患者的并发症。我们患者可能的危险因素包括既往高血压、术中失血、既往根治性颈清扫术导致静脉受压、术中头颈部水肿以及使用紧密贴合的塑料泡型术中眼部保护装置。本文描述了这种破坏性并发症的可能发病机制以及前部缺血性视神经病变的预防和管理建议。