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急诊科的小儿镇痛,我们做得对吗?

Paediatric analgesia in the emergency department, are we getting it right?

作者信息

Donald Colin, Duncan Russell, Blair Lorraine, Thakore Shobhan, Clark Michael

机构信息

Accident and Emergency, Ninewells Hospital, Dundee, Scotland, UK.

出版信息

Eur J Emerg Med. 2007 Jun;14(3):157-9. doi: 10.1097/MEJ.0b013e3280b17e36.

Abstract

OBJECTIVES

To measure the dose discrepancy in prescribing simple paediatric analgesia, in the emergency department, by comparing age and actual weight-based dosing. To establish the accuracy of the weight-estimation formula for children [weight kg=2 (age years+4)].

METHODS

A prospective survey conducted in the emergency departments of a UK teaching hospital and district general hospital. Two hundred and forty-seven children were prescribed simple analgesia in the form of paracetamol and ibuprofen or both. The dose prescribed was based on age. All children were weighed and a maximum dose based on the child's weight was calculated. The individual child's weight was also compared with the weight calculated using the estimation formula.

RESULTS

A total of 247 patients were included. Two hundred and thirty-three patients were prescribed paracetamol. Fifteen patients were prescribed ibuprofen. The paracetamol group was administered a mean dose that was 67% (P<0.001) of the optimal dose that was based on weight. Ibuprofen dosage was 51% (P<0.001) of optimal dose. The weight-estimation formula underestimated weight by 16% (P<0.001).

CONCLUSIONS

Prescribing analgesia by age often results in significant underdosing in the paediatric population. Predicting a child's weight using the calculation may result in underdosing.

摘要

目的

通过比较基于年龄和实际体重的给药剂量,测量急诊科开具简单儿科镇痛药物时的剂量差异。确定儿童体重估算公式[体重(千克)=2×(年龄+4)]的准确性。

方法

在英国一家教学医院和地区综合医院的急诊科进行一项前瞻性调查。247名儿童接受了对乙酰氨基酚和布洛芬形式的简单镇痛治疗,或两者皆用。所开剂量基于年龄。对所有儿童进行称重,并计算基于儿童体重的最大剂量。还将每个儿童的体重与使用估算公式计算出的体重进行比较。

结果

共纳入247例患者。233例患者接受了对乙酰氨基酚治疗。15例患者接受了布洛芬治疗。对乙酰氨基酚组的平均给药剂量为基于体重的最佳剂量的67%(P<0.001)。布洛芬剂量为最佳剂量的51%(P<0.001)。体重估算公式使体重低估了16%(P<0.001)。

结论

按年龄开具镇痛药物常常导致儿科患者用药剂量显著不足。使用该计算公式预测儿童体重可能导致用药剂量不足。

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