2-氯-6-（2-呋喃基）-9-（4-甲氧基苄基）-9H-嘌呤
2-Chloro-6-(2-furyl)-9-(4-methoxybenzyl)-9H-purine.
作者信息
Braendvang Morten, Gundersen Lise Lotte
机构信息
Department of Chemistry, University of Oslo, PO Box 1033, Blindern, N-0315 Oslo, Norway.
出版信息
Acta Crystallogr C. 2007 May;63(Pt 5):o274-6. doi: 10.1107/S0108270107011596. Epub 2007 Apr 14.
PMID:17478910
Abstract
The title compound, C(17)H(13)ClN(4)O(2), displays profound and selective activity against Mycobacterium tuberculosis. In the crystal structure, there are two independent molecules in the asymmetric unit. Intermolecular hydrogen bonding between a CH group of the purine ring and the O atom of the furan ring, and also pi-pi stacking in another direction, builds the three-dimensional network.
摘要
标题化合物C(17)H(13)ClN(4)O(2)对结核分枝杆菌显示出显著且具有选择性的活性。在晶体结构中，不对称单元中有两个独立的分子。嘌呤环的一个CH基团与呋喃环的O原子之间的分子间氢键，以及在另一个方向上的π-π堆积，构建了三维网络。
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