Adamopoulos Othon, Papadopoulos Triantafillos
Department of Materials Science and Engineering, Materials Chemistry Division, The Royal Institute of Technology, Brinellvägen 23, II, 100 44 Stockholm, Sweden.
J Mater Sci Mater Med. 2007 Aug;18(8):1587-97. doi: 10.1007/s10856-007-3041-6. Epub 2007 May 5.
Biomaterials science and technology have been expanding tremendously the recent years. The results of this evolution are obvious in maxillofacial applications especially with the contemporary development of Nanotechnology. Among biomaterials, bioceramics possess a specific field due to various interactions with the biological tissues. The combination of bioceramics and nanotechnology has resulted in enhanced skeletal interactions in maxillofacial applications. Nanotechnology secures better mechanical properties and more effective biological interactions with jaws. The main production methods for the synthesis of nanostructured materials include plasma arcing, chemical vapour deposition, sol-gel and precipitation. The bioceramics in Dentistry comprise inert, bioactive, resorbable and composite systems. The purpose of the present article is to describe the available nanotechnology methods and how these could be addressed to synthesise maxillofacial bioceramics with advanced properties for better biological applications. Additionally, it describes specific clinical applications in maxillofacial surgery of these biomaterials--either by themselves or in combination with others--that can be promising candidates for bone tissue engineering. Such applications include replacement of lost teeth, filling of jaws defects or reconstruction of mandible and temporomandibular joint.
近年来,生物材料科学与技术一直在大幅扩展。这种发展的成果在颌面应用中尤为明显,特别是随着纳米技术的当代发展。在生物材料中,生物陶瓷由于与生物组织的各种相互作用而占有特定领域。生物陶瓷与纳米技术的结合在颌面应用中增强了骨骼相互作用。纳米技术确保了更好的机械性能以及与颌骨更有效的生物相互作用。合成纳米结构材料的主要生产方法包括等离子电弧法、化学气相沉积法、溶胶 - 凝胶法和沉淀法。牙科中的生物陶瓷包括惰性、生物活性、可吸收和复合系统。本文的目的是描述现有的纳米技术方法,以及如何运用这些方法合成具有先进性能的颌面生物陶瓷以实现更好的生物应用。此外,本文还描述了这些生物材料在颌面外科中的特定临床应用——无论是单独使用还是与其他材料联合使用——这些应用有望成为骨组织工程的候选材料。此类应用包括缺失牙的替换、颌骨缺损的填充或下颌骨及颞下颌关节的重建。