Zhong L, Hu T, Liu M
Department of Pediatric Surgery, First Affiliated Hospital.
Hua Xi Yi Ke Da Xue Xue Bao. 1991 Sep;22(3):311-3.
In order to evaluate the factors in high-risk neonatal necrotizing enterocolitis (NEC) and predict the prognosis of NEC, a retrospective analysis of 32 factors was made in 42 neonates with NEC. The cases were divided into a low-risk (survival) group and a high-risk (death) group. Of 32 factors compared between these two group, eight were found to be of significance in evaluating the severity of NEC, and six of them were used in the development of a NEC scores (1) number of days before beginning of artificial feeding; (2) neonatal asphyxia or distress; (3) immature form in WBC differential; (4) CO2 combining power; (5) abdominal tenderness; (6) presence of portal vein air (PVA). All laboratory values and physical and radiographic signs were collected during initial presentation of NEC. Neonates with a score of 3 or more are at an increased risk of developing severe NEC with a 83% mortality.
为评估高危新生儿坏死性小肠结肠炎（NEC）的相关因素并预测NEC的预后，对42例NEC新生儿的32项因素进行了回顾性分析。将病例分为低风险（存活）组和高风险（死亡）组。在这两组之间比较的32项因素中，发现有8项在评估NEC严重程度方面具有显著意义，其中6项用于制定NEC评分：（1）开始人工喂养前的天数；（2）新生儿窒息或窘迫；（3）白细胞分类中的幼稚形式；（4）二氧化碳结合力；（5）腹部压痛；（6）门静脉积气（PVA）。所有实验室值以及体格检查和影像学体征均在NEC初次出现时收集。评分3分及以上的新生儿发生严重NEC的风险增加，死亡率为83%。
