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百岁老人的100例主动脉瓣置换术:早期死亡率的结果和危险因素

One-hundred aortic valve replacements in octogenarians: outcomes and risk factors for early mortality.

作者信息

Urso Stefano, Sadaba Rafael, Greco Ernesto, Pulitani Ivana, Alvarez Luis, Juaristi Arantxa, Goiti Juan J

机构信息

Policlinica Gipuzkoa, Cirugía Cardiaca, San Sebastian, Spain.

出版信息

J Heart Valve Dis. 2007 Mar;16(2):139-44.

Abstract

BACKGROUND AND AIM OF THE STUDY

Today, ageing of the western population is causing aortic valve surgery to be performed in elderly patients with increasing frequency. The study aim was to evaluate surgical outcome in octogenarian patients undergoing aortic valve replacement (AVR).

METHODS

A total of 100 patients (mean age 82.1 +/- 2.7 years; range: 80-95 years) who underwent AVR over a three-year period was reviewed. Concomitant coronary artery bypass grafting was performed in 34% of cases, and a bioprosthesis was implanted in 80%. The mean logistic EuroSCORE was 13.3%.

RESULTS

Operative mortality was 8.0%. In multivariate analysis, a logistic EuroSCORE > or =13.5% (p = 0.02), cross-clamp time > or =75 min (p = 0.02) and postoperative acute renal failure were predictors for in-hospital mortality. Follow up was 100% complete; the mean follow up period was 10.6 months. At one year after surgery, the actuarial survival rate of those patients who survived surgery was 86.1%. Postoperative dyspnea at one month (p = 0.004) was the only predictor of short-term mortality.

CONCLUSION

Age in itself should not contraindicate surgery, and healthcare systems should be prepared to accommodate elderly patients who may require special resources.

摘要

研究背景与目的

如今,西方人口老龄化导致主动脉瓣手术在老年患者中的实施频率日益增加。本研究旨在评估接受主动脉瓣置换术(AVR)的八旬老人的手术结局。

方法

回顾了在三年期间接受AVR的100例患者(平均年龄82.1±2.7岁;范围:80 - 95岁)。34%的病例同时进行了冠状动脉旁路移植术,80%植入了生物假体。平均逻辑欧洲心脏手术风险评估系统(EuroSCORE)为13.3%。

结果

手术死亡率为8.0%。多因素分析显示,逻辑EuroSCORE≥13.5%(p = 0.02)、主动脉阻断时间≥75分钟(p = 0.02)和术后急性肾衰竭是院内死亡的预测因素。随访完成率为100%;平均随访期为10.6个月。术后1年,手术存活患者的精算生存率为86.1%。术后1个月的呼吸困难(p = 0.004)是短期死亡的唯一预测因素。

结论

年龄本身不应成为手术禁忌,医疗系统应做好准备,接纳可能需要特殊资源的老年患者。

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