Palys Erica E, Li John, Gaut Paula L, Hardy W David
Division of Infectious Diseases, Cedars-Sinai Medical Center, Becker 220, Los Angeles, CA 90048, USA.
Infect Dis Obstet Gynecol. 2006;2006:43253. doi: 10.1155/IDOG/2006/43253.
Streptococcus agalactiae, commonly known as Group B streptococcus (GBS), was originally discovered as a cause of bovine mastitis. GBS colonizes the genital tract of up to 40% of women and has become a major pathogen in neonatal meningitis. GBS endocarditis is thought to be an uncommon manifestation of this infection and carries a higher mortality compared to other streptococcal pathogens. Studies have shown that endocarditis after abortion has an incidence of about one per million. However, this figure was published prior to routine use of echocardiography for diagnosis. The American Heart Association has recently declared transesophageal echocardiography the gold standard for endocarditis diagnosis. This case report illustrates that, given the potentially devastating consequences of endocarditis, there is a need for updated studies to adequately assess the true incidence of this infection. Pending the outcome of these studies, routine GBS screening and prophylactic antibiotics prior to abortion should be recommended.
无乳链球菌，通常称为B组链球菌（GBS），最初是作为牛乳腺炎的病因被发现的。GBS定植于高达40%的女性生殖道，已成为新生儿脑膜炎的主要病原体。GBS心内膜炎被认为是这种感染的一种罕见表现，与其他链球菌病原体相比，其死亡率更高。研究表明，流产后心内膜炎的发病率约为百万分之一。然而，这个数字是在常规使用超声心动图进行诊断之前公布的。美国心脏协会最近宣布经食管超声心动图是心内膜炎诊断的金标准。本病例报告表明，鉴于心内膜炎可能带来的毁灭性后果，需要进行更新的研究以充分评估这种感染的真实发病率。在这些研究结果出来之前，建议在流产前进行常规GBS筛查和预防性使用抗生素。
