Rikimaru Toru, Yonemitu Junko, Shimada Akiko, Makimoto Yoshihumi, Aizawa Hisamichi
Department of Respiratory Medicine, Kurume University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2007 Apr;45(4):306-13.
To clarify whether the environment of a nursing home affects the clinical features of patients with pneumonia, we compared the characteristics of 103 patients (nursing home group) who suffered from pneumonia at a nursing home with 153 elderly patients with the same background (community group) who lived in their own home. Although there were no significant differences in CRP, WBC, and body temperature at admission and duration of hospitalization, the degree of independency of the nursing home group was significantly lower than the community group. As the degree of independency became worse, the length of hospitalization extended and mortality increased. Bacteriological findings of sputum culture showed that methicillin-resistant Staphylococcus aureus (MRSA) was cultured in 20 cases (19%) of the nursing home group and 18 cases (13%) of the community group. In isolated analysis of total care cases, MRSA positive rates were similar in the nursing home group (17/58; 29%) and the community group (8/30; 27%). Only 1 case with penicillin-susceptible Streptococcus pneumoniae (PSSP) was found in the nursing home group, however 7 species of PSSP were cultured in the community group, including 5 self-help cases. Pseudomonas aeruginosa was cultured in 8 patients of each group, and most of them were total care cases. We concluded that the difference in frequency and species of bacteria depended on the condition of patients, rather than the environment, and differences in conditions might lead to differences in clinical features.
为了阐明养老院环境是否会影响肺炎患者的临床特征,我们将103例在养老院患肺炎的患者(养老院组)的特征与153例背景相同、居家生活的老年患者(社区组)进行了比较。尽管入院时的CRP、白细胞和体温以及住院时间没有显著差异,但养老院组的独立程度明显低于社区组。随着独立程度变差,住院时间延长且死亡率增加。痰培养的细菌学结果显示,养老院组20例(19%)培养出耐甲氧西林金黄色葡萄球菌(MRSA),社区组18例(13%)培养出该菌。在对全护理病例的单独分析中,养老院组(17/58;29%)和社区组(8/30;27%)的MRSA阳性率相似。养老院组仅发现1例青霉素敏感肺炎链球菌(PSSP),而社区组培养出7种PSSP,其中包括5例自理病例。每组各有8例患者培养出铜绿假单胞菌,且大多数为全护理病例。我们得出结论,细菌的频率和种类差异取决于患者状况而非环境,状况差异可能导致临床特征的差异。