Stanek Christian
Institut für Radioonkologie, Wilhelminenspital der Stadt Wien, Wien, Osterreich.
Wien Med Wochenschr. 2007;157(7-8):149-52. doi: 10.1007/s10354-007-0404-z.
Depending on tumor-stage and risk-factors, prostate cancer can be treated by Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, Androgen Ablation or a combination of at least two of them. In clinically localized low-risk cases, the results of radiotherapy and surgery are very similar. Patients with intermediate-risk or high-risk prostate cancer, often not suited for radical prostatectomy, seem to benefit from higher radiation doses and additional Androgen ablation, although questions remain regarding the treatment volume of radiotherapy and the optimal timing and duration of androgen deprivation. Standardised target volume definitions and dose prescriptions for different risk groups and improved patient selection for radiotherapy are required.
根据肿瘤分期和风险因素,前列腺癌可通过根治性前列腺切除术、外照射放疗、近距离放疗、雄激素剥夺治疗或至少两种方法联合治疗。在临床局限性低风险病例中,放疗和手术的效果非常相似。中风险或高风险前列腺癌患者通常不适合根治性前列腺切除术,似乎能从更高的辐射剂量和额外的雄激素剥夺治疗中获益,尽管关于放疗的治疗体积以及雄激素剥夺的最佳时机和持续时间仍存在问题。需要针对不同风险组制定标准化的靶体积定义和剂量处方,并改善放疗患者的选择。