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二尖瓣脱垂所致慢性二尖瓣反流患者行二尖瓣修复时的瓣环与瓣叶不匹配及缩窄性瓣环成形术的必要性。

Annular-to-leaflet mismatch and the need for reductive annuloplasty in patients undergoing mitral repair for chronic mitral regurgitation due to mitral valve prolapse.

作者信息

Maisano Francesco, La Canna Giovanni, Grimaldi Antonio, Viganò Giorgio, Blasio Andrea, Mignatti Andrea, Colombo Antonio, Maseri Attilio, Alfieri Ottavio

机构信息

Department of Cardiac Surgery, San Raffaele University Hospital, Milan, Italy.

出版信息

Am J Cardiol. 2007 May 15;99(10):1434-9. doi: 10.1016/j.amjcard.2006.12.072. Epub 2007 Apr 4.

Abstract

Annular dilation is a common feature of chronic degenerative mitral regurgitation caused by leaflet prolapse. Accordingly, patients undergoing surgical repair usually undergo concomitant reductive annuloplasty to restore a normal annular-to-leaflet relation. With the evolution of transcatheter valve repair technologies, patient selection criteria for those who do not require annuloplasty are needed. A series of patients undergoing mitral repair was analyzed, and the role of annular-to-leaflet mismatch in identifying patients requiring reductive annuloplasty was explored. Preoperative data for 82 patients undergoing mitral repair with annuloplasty for degenerative mitral regurgitation were prospectively collected, including annular intercommissural (IC) and septolateral (SL) dimensions and heights of anterior (ALH) and posterior leaflets. An SL/ALH ratio >1.4 was used to define annular-to-leaflet mismatch. After mitral repair, the ratio between preoperative IC distance and the size of the implanted annular prosthesis (Seguin ring [SR], IC/SR <1.2) was used to identify patients for whom annuloplasty was nonreductive. All patients underwent successful mitral repair. Mean preoperative IC was 46 +/- 6 mm, SL was 42 +/- 5 mm, and ALH was 31 +/- 5 mm. Mean SR was 34 +/- 3 mm, with a mean IC/SR ratio of 1.34 +/- 0.14. Sixteen patients (19%) had an IC/SR ratio <1.2. IC/SR ratio <1.2 was predicted by a SL/ALH ratio < or =1.4 (p = 0.009). In conclusion, annular dilation is negligible in <20% of surgical candidates. In this subgroup, an isolated leaflet repair may be indicated. SL/ALH ratio is a good indicator of annular-to-leaflet mismatch and could be used as an adjunct to other methods of annular function assessment to select patients for ringless mitral repair.

摘要

瓣环扩张是由瓣叶脱垂引起的慢性退行性二尖瓣反流的常见特征。因此,接受手术修复的患者通常同时进行缩窄性瓣环成形术,以恢复正常的瓣环与瓣叶关系。随着经导管瓣膜修复技术的发展,需要确定不需要进行瓣环成形术的患者选择标准。对一系列接受二尖瓣修复的患者进行了分析,并探讨了瓣环与瓣叶不匹配在识别需要缩窄性瓣环成形术患者中的作用。前瞻性收集了82例因退行性二尖瓣反流接受二尖瓣修复及瓣环成形术患者的术前数据,包括瓣环 commissural(IC)和 septolateral(SL)尺寸以及前叶(ALH)和后叶高度。SL/ALH 比值>1.4 用于定义瓣环与瓣叶不匹配。二尖瓣修复后,术前 IC 距离与植入的瓣环假体大小(Seguin 环[SR],IC/SR<1.2)之间的比值用于识别瓣环成形术为非缩窄性的患者。所有患者二尖瓣修复均成功。术前平均 IC 为 46±6mm,SL 为 42±5mm,ALH 为 31±5mm。平均 SR 为 34±3mm,平均 IC/SR 比值为 1.34±0.14。16 例患者(19%)的 IC/SR 比值<1.2。SL/ALH 比值≤1.4 可预测 IC/SR 比值<1.2(p = 0.009)。总之,在<20%的手术候选患者中,瓣环扩张可忽略不计。在该亚组中,可能适合单纯瓣叶修复。SL/ALH 比值是瓣环与瓣叶不匹配的良好指标,可作为评估瓣环功能的其他方法的辅助手段,用于选择无环二尖瓣修复的患者。

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