Ebrahimi N, Claus B, Lee C-Y, Biondi A, Benndorf G
Biomechanical Engineering Program, University of Houston, Houston, TX, USA.
AJNR Am J Neuroradiol. 2007 May;28(5):823-9.
Radiographic visibility of self-expandable intracranial stents is insufficient for assessment of conformability and deployment characteristics. The purpose of this study was to evaluate stent mechanics in a curved vessel model by using Flat-Panel CT (FPCT).
The following stents were used: Neuroform 2, Neuroform Treo, Enterprise, and LEO. All stents were bent in the same polytetrafluoroethylene tubes with various angles ranging from 150 degrees to 30 degrees . To visualize potential prolapse of the stent struts, 4-, 5-, and 8-mm openings were created. FPCTs were obtained using a C-arm with flat detector.
FPCT scans provided excellent visualization of deployment characteristics and stent mechanics and was superior to digital subtraction angiography (DSA) and digital radiography (DR). The Neuroform2/Treo showed, with increasing angle and diameter of the opening, a continuous increase in cell size. These stents also showed an outward prolapse at the convexity and an inwards prolapse of struts at the concavity of the curvature. The Enterprise showed an increasing trend to flatten and to kink with curvatures that are more acute. The LEO showed fewer trends to kink but an inward crimping of its ends with more acute angles.
Deployment characteristics and conformability to a curved vessel model vary considerably, depending on the angle and the stent design. Adverse mechanics such as increased cell opening, strut prolapse, flattening, and kinking occur during stent placement in a curved vessel model, and may gain clinical importance. FPCT is superior to DSA and DR in visualizing small metallic stents and enables accurate detection of adverse stent mechanics.
自膨式颅内支架的影像学可视性不足以评估其贴壁性和展开特性。本研究的目的是通过使用平板CT(FPCT)评估弯曲血管模型中的支架力学性能。
使用以下支架:Neuroform 2、Neuroform Treo、Enterprise和LEO。所有支架均在相同的聚四氟乙烯管中弯曲,弯曲角度范围为150度至30度。为了观察支架支柱的潜在脱垂情况,制作了4毫米、5毫米和8毫米的开口。使用带有平板探测器的C形臂获取FPCT图像。
FPCT扫描能够出色地显示支架的展开特性和力学性能,优于数字减影血管造影(DSA)和数字X线摄影(DR)。随着开口角度和直径的增加,Neuroform2/Treo的网眼尺寸持续增大。这些支架在弯曲的凸面处还显示出向外脱垂,在凹面处支柱向内脱垂。Enterprise随着弯曲度变得更急,有逐渐变平并扭结的趋势。LEO扭结的趋势较少,但在角度更急时其两端会向内卷曲。
在弯曲血管模型中的展开特性和贴壁性因角度和支架设计的不同而有很大差异。在弯曲血管模型中放置支架时会出现诸如网眼增大、支柱脱垂、变平及扭结等不良力学情况,且可能具有临床重要性。在显示小型金属支架方面,FPCT优于DSA和DR,能够准确检测出不良的支架力学情况。