Puscheck Elizabeth E, Jeyendran Rajasingam S
Wayne State University Medical School, University Women's Care, Division of Reproductive Endocrine and Infertility, Detroit, Michigan 48201, USA.
Curr Opin Obstet Gynecol. 2007 Jun;19(3):222-8. doi: 10.1097/GCO.0b013e32813e3ff0.
The present paper reviews the current literature on the impact of male factor on recurrent pregnancy loss.
Most clinicians focus their evaluation of recurrent pregnancy loss on the female, without much, if any, consideration of the other half of the couple - the male. Yet, the male contributes one-half of the genes for the embryo. Recent literature demonstrates that the male contributes to recurrent pregnancy loss due to genetic factors, semen factors or due to other factors such as age.
Recurrent pregnancy loss results as a factor of a couple. This paper emphasizes the contribution of the male to implantation failure, miscarriage, and congenital anomalies suggested by recent literature. The current data are preliminary. With further investigation, evaluation of the male may be considered a routine part of the evaluation in the near future.
本文综述了当前关于男性因素对复发性流产影响的文献。
大多数临床医生在评估复发性流产时主要关注女性,而很少(如果有的话)考虑夫妻中的另一半——男性。然而,男性为胚胎贡献了一半的基因。最近的文献表明,男性因遗传因素、精液因素或其他因素(如年龄)导致复发性流产。
复发性流产是夫妻双方共同作用的结果。本文强调了近期文献所表明的男性在植入失败、流产和先天性异常方面的作用。目前的数据是初步的。随着进一步的研究,对男性的评估可能在不久的将来被视为评估的常规部分。