Aguirre Anna Rita, Balbo Bruno Eduardo Pedroso, Ianhez Luiz Estevam, da Costa Maristela Carvalho, Andrade Lúcia
Intensive Care Unit, Nephrology Department, University of São Paulo School of Medicine, São Paulo, Brazil.
Ren Fail. 2007;29(4):513-6. doi: 10.1080/08860220701275014.
Pneumocystis carinii pneumonia is a serious and relatively common complication of immunosuppressive therapy. In immunocompromised patients, P. carinii pneumonia can cause significant morbidity and mortality. Another common complication, typically seen in the subpopulation of renal transplant recipients, is hypercalcemia. The prevalence of hypercalcemia varies, reaching as high as 71%. We report the case of a renal transplant recipient who developed P. carinii pneumonia and hypercalcemia, the latter being resolved after the successful treatment of the former. We argue that there is a causal relationship between P. carinii pneumonia and hypercalcemia in renal transplant recipients. In immunocompromised patients, pulmonary infection accompanied by hypercalcemia should raise the suspicion of P. carinii pneumonia.
卡氏肺孢子虫肺炎是免疫抑制治疗的一种严重且相对常见的并发症。在免疫功能低下的患者中,卡氏肺孢子虫肺炎可导致显著的发病率和死亡率。另一种常见并发症,通常见于肾移植受者亚群,是高钙血症。高钙血症的患病率各不相同,高达71%。我们报告一例肾移植受者发生卡氏肺孢子虫肺炎和高钙血症的病例,后者在前者成功治疗后得到缓解。我们认为肾移植受者中卡氏肺孢子虫肺炎与高钙血症之间存在因果关系。在免疫功能低下的患者中,伴有高钙血症的肺部感染应怀疑为卡氏肺孢子虫肺炎。