Pavlović Aleksandra M, Covicković-Sternić Nadezda
Srp Arh Celok Lek. 2007 Jan-Feb;135(1-2):92-7.
Huge steps forward in understanding and treatment of ischemic stroke happened in the last several decades. Significant part of this progress is due to advances in diagnostic possibilities, with the leading role of transcranial Doppler (TCD). The American Academy of Neurology has recently published new guidelines and indications for TCD use. Indications with the highest rank, when TCD is able to provide information with established clinical utility, are designated as follows: (1) screening of children aged 2 to 16 years with sickle cell disease for assessing the stroke risk, and (2) detection and monitoring of vasospasm in spontaneous subarachnoid hemorrhage. TCD indications in setting where this examination provides important information but with still indefinite clinical utility are: (1) intracranial steno-occlusive disease, with data insufficient to recommend replacement of conventional angiography with TCD, despite obvious TCD usefulness and precision, and (2) cerebral circulatory arrest detection, as confirmatory test in support of clinical diagnosis of brain death. The major limiting factor of TCD application is dependence on an examiner's training and skills. Only strict application of diagnostic protocols and accepted criteria, with knowledge of pathophysiologic basis of cerebrovascular diseases and TCD principles, can result in conclusive findings. TCD is the source of valuable information for neurologists and other specialty physicians. This text presents review of other TCD indications and their application in everyday practice.
在过去几十年里,缺血性中风的理解和治疗取得了巨大进展。这一进展的很大一部分归功于诊断可能性的进步,其中经颅多普勒(TCD)起了主导作用。美国神经病学学会最近发布了TCD使用的新指南和适应症。当TCD能够提供具有既定临床效用的信息时,具有最高等级的适应症如下:(1)对2至16岁镰状细胞病患儿进行中风风险评估筛查,以及(2)检测和监测自发性蛛网膜下腔出血中的血管痉挛。在TCD检查能提供重要信息但临床效用仍不确定的情况下,TCD的适应症有:(1)颅内狭窄闭塞性疾病,尽管TCD明显有用且精确,但数据不足以推荐用TCD替代传统血管造影,以及(2)脑循环骤停检测,作为支持脑死亡临床诊断的确认性检查。TCD应用的主要限制因素是依赖检查者的培训和技能。只有严格应用诊断方案和公认标准,了解脑血管疾病的病理生理基础和TCD原理,才能得出确凿的结果。TCD是神经科医生和其他专科医生获取有价值信息的来源。本文介绍了TCD的其他适应症及其在日常实践中的应用。