Distribution of CCR2 polymorphism in HIV-1-infected and healthy subjects in North India.
作者信息
Kaur G, Singh P, Kumar N, Rapthap C C, Sharma G, Vajpayee M, Wig N, Sharma S K, Mehra N K
机构信息
Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
出版信息
Int J Immunogenet. 2007 Jun;34(3):153-6. doi: 10.1111/j.1744-313X.2007.00667.x.
Abstract
Substitution of V64I in CCR2 relates to delayed progression to AIDS and protects against HIV-1 infection. We examined the distribution of V64I in HIV-infected and healthy North Indian subjects. No significant difference in the allele or genotype distribution of CCR2 V64I polymorphism was observed, indicating that there is no association between CCR2 V64I polymorphism and susceptibility to HIV infection in North Indian population.
摘要
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