Alves Maria Júlia M, Colli Walter
Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
IUBMB Life. 2007 Apr-May;59(4-5):274-9. doi: 10.1080/15216540701200084.
Both invasion of the host cell by T. cruzi and its establishment into the mammalian host are critical steps. In this review, the adhesion step and the intracellular survival in non-professional phagocytes are particularly focused on, with special emphasis on the role of Gp85/trans-sialidase (Gp85/TS) superfamily. Excellent reviews have been published lately, some covering other aspects of T. cruzi-host interaction and will be cited instead of the original articles due to limited number of listed references.
克氏锥虫对宿主细胞的侵袭及其在哺乳动物宿主体内的定植都是关键步骤。在本综述中,特别关注了非专职吞噬细胞中的黏附步骤和细胞内存活,尤其强调了Gp85/转唾液酸酶(Gp85/TS)超家族的作用。最近已经发表了一些优秀的综述,其中一些涵盖了克氏锥虫与宿主相互作用的其他方面,由于列出的参考文献数量有限,将引用这些综述而非原始文章。