Wallen Eric M, Pruthi Raj S, Joyce Geoffrey F, Wise Matthew
Division of Urology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
J Urol. 2007 Jun;177(6):2006-18; discussion 2018-9. doi: 10.1016/j.juro.2007.01.126.
We quantified the burden of kidney cancer in the United States by identifying trends in the use of health care resources and estimating the economic impact of the disease.
The analytical methods used to generate these results were described previously.
The incidence of all stages of kidney cancer is increasing in America, particularly T1 disease. Rates are increasing more rapidly in the black than in the white population and survival is worse for black individuals at all stages of diagnosis. Total expenditures for kidney cancer were $401 million in 2000, representing a 46% increase from 1994. Approximately 85% of health care dollars spent on kidney cancer were for inpatient care with steady increases through the 1990s. Regarding treatment, more partial nephrectomies were performed in Medicare patients as the 1990s progressed. Health Care Cost and Utilization Project data showed an increase in the number of inpatient hospitalizations but this trend was not seen in the Centers for Medicare and Medicaid Services data set. Length of stay decreased from 1994 to 2000 in the Health Care Cost and Utilization Project database. The adoption of laparoscopic techniques began to appear in the Veterans Affairs data set in 2001 and it increased thereafter.
Increasing trends in the incidence of and costs associated with kidney cancer have been apparent for more than 10 years. As the population ages and the prevalence of risk factors such as obesity and hypertension increases, the burden of disease will increase significantly. Consideration should be given to expanding tumor registries such as Surveillance, Epidemiology and End Results. Treatment databases could better characterize the cost and effectiveness of treatment for metastatic disease and of trends in the adoption of laparoscopy.
我们通过确定医疗保健资源使用趋势并估算该疾病的经济影响,来量化美国肾癌的负担。
先前已描述用于得出这些结果的分析方法。
美国各阶段肾癌的发病率均在上升,尤其是T1期疾病。黑人的发病率增长速度比白人更快,且在所有诊断阶段,黑人的生存率都更低。2000年肾癌的总支出为4.01亿美元,比1994年增长了46%。20世纪90年代,用于肾癌的医疗保健费用中约85%用于住院治疗,且费用持续增加。在治疗方面,随着20世纪90年代的推进,医疗保险患者中进行部分肾切除术的人数增多。医疗保健成本与利用项目数据显示住院人数有所增加,但医疗保险和医疗补助服务中心的数据集中未出现这一趋势。在医疗保健成本与利用项目数据库中,住院时间从1994年至2000年有所缩短。2001年退伍军人事务部的数据集中开始出现腹腔镜技术的应用,此后应用量有所增加。
肾癌发病率及相关成本的上升趋势在10多年来一直很明显。随着人口老龄化以及肥胖和高血压等风险因素的患病率增加,疾病负担将显著加重。应考虑扩大肿瘤登记处,如监测、流行病学和最终结果登记处。治疗数据库可以更好地描述转移性疾病治疗的成本和效果以及腹腔镜技术应用的趋势。