一例复杂部分性癫痫持续状态后海马层状坏死病例。
A case of hippocampal laminar necrosis following complex partial status epilepticus.
作者信息
Heinrich A, Runge U, Kirsch M, Khaw A V
机构信息
Department of Neurology, University of Greifswald, Greifswald, Germany.
出版信息
Acta Neurol Scand. 2007 Jun;115(6):425-8. doi: 10.1111/j.1600-0404.2006.00784.x.
Cortical laminar necrosis (CLN) is a metabolic injury pattern usually observed after cerebral hypoxia, hypoglycemia, or ischemia. We report serial magnetic resonance imaging findings in a patient with complex partial status epilepticus (SE) developing a band-like, T1-hyperintense lesion consistent with CLN along the surface of the left hippocampus without concurrent other causes of CLN. This observation suggests a direct pathogenetic link between SE and CLN involving combined damage to neurons and glia.
皮质层状坏死（CLN）是一种通常在脑缺氧、低血糖或缺血后观察到的代谢性损伤模式。我们报告了一名复杂性部分性癫痫持续状态（SE）患者的系列磁共振成像结果，该患者在左侧海马表面出现了与CLN一致的带状T1高信号病变，且无并发CLN的其他原因。这一观察结果提示SE与CLN之间存在直接的发病机制联系，涉及神经元和神经胶质的联合损伤。
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