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[缺血性中风和短暂性脑缺血发作后的二级预防]

[Secondary prophylaxis after ischemic stroke and transitoric ischemic attack].

作者信息

Russell David, Lund Christian, Dahl Arve

机构信息

Cerebrovaskulaer seksjon, Nevrologisk avdeling, Nevroklinikken, Rikshospitalet-Radiumhospitalet, 0027 Oslo.

出版信息

Tidsskr Nor Laegeforen. 2007 May 17;127(10):1379-82.

Abstract

BACKGROUND

Approximately 13,000 persons develop a stroke in Norway each year. 3,000 of these are recurrent strokes. There are also more than 10,000 patients who experience a transitory ischemic attack each year which often immediately precedes a stroke. The aim of this review article is to present updated treatment recommendations for secondary prophylaxis after an ischemic stroke or TIA.

MATERIAL AND METHODS

This article is based on the guidelines from the European Stroke Initiative, the American Stroke Association and review articles found by searching Medline and the Cochrane database. New relevant randomized studies are also included and discussed. Therapy guidelines have been modified for Norwegian use.

RESULTS AND INTERPRETATION

Individualised secondary prophylaxis following an ischemic stroke or TIA can prevent cerebrovascular disease and death. It is especially important with optimal blood pressure and blood glucose control as well as adequate antithrombotic and lipid-lowering treatment.

摘要

背景

挪威每年约有13000人发生中风。其中3000例为复发性中风。每年还有超过10000名患者经历短暂性脑缺血发作,这通常是中风的先兆。这篇综述文章的目的是提出缺血性中风或短暂性脑缺血发作后二级预防的最新治疗建议。

材料与方法

本文基于欧洲中风倡议、美国中风协会的指南以及通过检索Medline和Cochrane数据库找到的综述文章。还纳入并讨论了新的相关随机研究。治疗指南已针对挪威的情况进行了修改。

结果与解读

缺血性中风或短暂性脑缺血发作后的个体化二级预防可预防脑血管疾病和死亡。最佳的血压和血糖控制以及充分的抗血栓和降脂治疗尤为重要。

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