在中国，至少有两种基因不同的大型巴贝斯虫可感染绵羊和山羊。
At least two genetically distinct large Babesia species infective to sheep and goats in China.
作者信息
Liu A H, Yin H, Guan G Q, Schnittger L, Liu Z J, Ma M L, Dang Z S, Liu J L, Ren Q Y, Bai Q, Ahmed J S, Luo J X
机构信息
State Key Laboratory of Veterinary Etiological Biology & Gansu Provincal Key Laboratory of Veterinary Parasitology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 11, Lanzhou, Gansu 730046, China.
出版信息
Vet Parasitol. 2007 Jul 20;147(3-4):246-51. doi: 10.1016/j.vetpar.2007.03.032. Epub 2007 May 24.
A fatal disease of sheep and goats in the northern part of China has been reported to be due to Babesia ovis. However, some characteristics of the causative agent in recent reports are not in accordance with the original attributes ascribed to this parasite. Therefore, the 18S small subunit ribosomal RNA (18S rRNA) genes of a number of Babesia isolates in China were sequenced and compared with that of other Babesia and Theileria species in an attempt to clarify their taxonomic position. In the present study, seven Babesia isolates were collected from distinct areas of northern China, and the 18S rRNA genes were amplified and sequenced. The phylogenetic trees were inferred based on 18S rRNA gene sequences of the Chinese ovine Babesia isolates and some of ovine Babesia and Theileria species available in GenBank. In the phylogenetic tree, Babesia sp. isolates from Madang, Tianzhu, Lintan, Ningxian, Hebei and Liaoning all grouped with B. motasi with 88.2-99.9% identity, while Babesia sp. Xinjiang grouped in a separate clade between B. ovis and B. crassa with 79.7-81.2% identity. The results indicated that there are at least two distinct Babesia species groups-B. motasi and Babesia sp. Xinjiang, the latter was distinctly different from other ovine Babesia isolates from China with less than 86.6% identity.
据报道，中国北方绵羊和山羊的一种致命疾病是由绵羊巴贝斯虫引起的。然而，近期报告中病原体的一些特征与最初赋予该寄生虫的属性不符。因此，对中国一些巴贝斯虫分离株的18S小亚基核糖体RNA（18S rRNA）基因进行了测序，并与其他巴贝斯虫和泰勒虫物种的基因进行比较，以明确它们的分类地位。在本研究中，从中国北方不同地区收集了7株巴贝斯虫分离株，对其18S rRNA基因进行扩增和测序。基于中国绵羊巴贝斯虫分离株以及GenBank中一些绵羊巴贝斯虫和泰勒虫物种的18S rRNA基因序列构建了系统发育树。在系统发育树中，来自玛曲、天祝、临潭、宁县、河北和辽宁的巴贝斯虫分离株均与莫氏巴贝斯虫聚类，同源性为88.2%-99.9%，而新疆巴贝斯虫分离株聚在一个单独的分支中，位于绵羊巴贝斯虫和粗壮巴贝斯虫之间，同源性为79.7%-81.2%。结果表明，至少存在两个不同的巴贝斯虫物种群——莫氏巴贝斯虫和新疆巴贝斯虫，后者与中国其他绵羊巴贝斯虫分离株明显不同，同源性低于86.6%。
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