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复发性早产

Recurrent preterm birth.

作者信息

Mazaki-Tovi Shali, Romero Roberto, Kusanovic Juan Pedro, Erez Offer, Pineles Beth L, Gotsch Francesca, Mittal Pooja, Than Nandor Gabor, Espinoza Jimmy, Hassan Sonia S

机构信息

Perinatology Research Branch, Intramural Division, NICHD/NIH/DHHS, Hutzel Women's Hospital, Bethesda, MD, USA.

出版信息

Semin Perinatol. 2007 Jun;31(3):142-58. doi: 10.1053/j.semperi.2007.04.001.

Abstract

Recurrent preterm birth is frequently defined as two or more deliveries before 37 completed weeks of gestation. The recurrence rate varies as a function of the antecedent for preterm birth: spontaneous versus indicated. Spontaneous preterm birth is the result of either preterm labor with intact membranes or preterm prelabor rupture of the membranes. This article reviews the body of literature describing the risk of recurrence of spontaneous and indicated preterm birth. Also discussed are the factors which modify the risk for recurrent spontaneous preterm birth (a short sonographic cervical length and a positive cervicovaginal fetal fibronectin test). Patients with a history of an indicated preterm birth are at risk not only for recurrence of this subtype, but also for spontaneous preterm birth. Individuals of black origin have a higher rate of recurrent preterm birth.

摘要

复发性早产通常定义为妊娠满37周前发生两次或更多次分娩。复发率因早产的原因而异:自发性早产与医源性早产。自发性早产是胎膜完整的早产宫缩或临产前胎膜早破的结果。本文综述了描述自发性早产和医源性早产复发风险的文献。还讨论了可改变复发性自发性早产风险的因素(超声测量宫颈长度短和宫颈阴道胎儿纤维连接蛋白检测呈阳性)。有医源性早产病史的患者不仅有这种亚型复发的风险,也有自发性早产的风险。黑人血统的个体复发性早产率较高。

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