Koziel Slawomir, Ulijaszek Stanley J, Szklarska Alicja, Bielicki Tadeusz
Institute of Anthropology, Polish Academy of Sciences, Kuznicza 35, 50-951 Wroclaw, Poland.
Ann Hum Biol. 2007 Jan-Feb;34(1):123-31. doi: 10.1080/03014460601121795.
Inverse relationships between respiratory function and indices of obesity and fat distribution have been reported, but it remains unclear which measure of obesity shows the strongest relationship with lung function.
The study assessed the effect of fatness and fat distribution on respiratory function.
A sample of 423 males and 509 females aged 40-50 years were examined in the Silesian Centre for Preventive Medicine, DOLMED, in Wrocław in 1995. The strength of influence of height, body mass index (BMI), wait-to-hip ratio (WHR) and abdominal and subscapular skinfolds upon forced vital capacity (FVC) and forced expiratory volume in a 1-s expiration (FEV1) was assessed by multiple regression analysis.
In males, FVC was strongly positively associated with height and BMI, but negatively associated with subscapular and abdominal skinfolds, WHR, and smoking. FEV1 showed a positive relationship with height, BMI and WHR. In females, both FVC and FEV1 showed significant positive associations with height, negative ones with subscapular skinfold, and no association with either WHR or abdominal skinfold. In males, respiratory function is affected to a similar extent by fat in the abdominal region and by fatness of the chest. In females, fatness of the thorax has the strongest relationship with respiratory function.
Fatness tends to impair respiratory function in both sexes but these effects show a different pattern in males and females. In males, respiratory functions are significantly, and to a similar extant, affected by fatness in the abdominal region, both subcutaneous and visceral, and by fatness on the chest. In females, it is primarily subcutaneous fat on the upper thorax that affects respiratory functions, while visceral and subcutaneous abdominal fatness play little or no role.
已有报道称呼吸功能与肥胖及脂肪分布指标之间存在负相关关系，但尚不清楚哪种肥胖指标与肺功能的关系最为密切。
本研究评估肥胖程度和脂肪分布对呼吸功能的影响。
1995年，在弗罗茨瓦夫的西里西亚预防医学中心DOLMED对423名年龄在40至50岁之间的男性和509名女性进行了检查。通过多元回归分析评估身高、体重指数（BMI）、腰臀比（WHR）以及腹部和肩胛下皮褶厚度对用力肺活量（FVC）和第1秒用力呼气量（FEV1）的影响强度。
在男性中，FVC与身高和BMI呈强正相关，但与肩胛下和腹部皮褶厚度、WHR以及吸烟呈负相关。FEV1与身高、BMI和WHR呈正相关。在女性中，FVC和FEV1均与身高呈显著正相关，与肩胛下皮褶厚度呈负相关，与WHR或腹部皮褶厚度均无关联。在男性中，腹部脂肪和胸部脂肪对呼吸功能的影响程度相似。在女性中，胸部脂肪与呼吸功能的关系最为密切。
肥胖往往会损害两性的呼吸功能，但这些影响在男性和女性中表现出不同的模式。在男性中，呼吸功能受到腹部皮下和内脏脂肪以及胸部脂肪的显著影响，且影响程度相似。在女性中，主要是上胸部的皮下脂肪影响呼吸功能，而腹部内脏和皮下脂肪的作用很小或没有作用。
