Richter Holly E, Goode Patricia S, Kenton Kim, Brown Morton B, Burgio Kathryn L, Kreder Karl, Moalli Pamela, Wright E James, Weber Anne M
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
J Am Geriatr Soc. 2007 Jun;55(6):857-63. doi: 10.1111/j.1532-5415.2007.01178.x.
To compare perioperative morbidity and 1-year outcomes of older and younger women undergoing surgery for pelvic organ prolapse (POP).
Prospective ancillary analysis.
Academic medical centers in National Institutes of Health, National Institute of Child Health and Human Development Colpopexy and Urinary Reduction Study.
Women with POP and no symptoms of stress incontinence.
Abdominal sacrocolpopexy with randomization to receive Burch colposuspension for treatment of possible occult incontinence or not.
Perioperative complications and Pelvic Organ Prolapse Quantification and quality-of-life (QOL) questionnaires (Pelvic Floor Distress Inventory, Pelvic Floor Impact Questionnaire, and Medical Outcomes Study Short-Form Health Survey (SF-36) preoperatively, immediately postoperatively, and 6 weeks and 3 and 12 months postoperatively).
Three hundred twenty-two women aged 31 to 82 (21% aged > or =70), 93% white. Older women had higher baseline comorbidity (P<.001) and more severe POP (P=.003). Controlling for prolapse stage and whether Burch was performed, there were no age differences in complication rates. Older women had longer hospital stays (3.1+/-1.0 vs 2.7+/-1.5 days, P=.02) and higher prevalence of incontinence at 6 weeks (54.7% vs 37.2%, P=.005). At 3 and 12 months, there were no differences in self-reported incontinence, stress testing for incontinence, or prolapse stage. Improvements from baseline were significant on all QOL measures but with no age differences.
Outcomes of prolapse surgery were comparable between older and younger women except that older women had slightly longer hospital stays.
比较接受盆腔器官脱垂(POP)手术的老年和年轻女性的围手术期发病率及1年预后。
前瞻性辅助分析。
美国国立卫生研究院、国家儿童健康与人类发展研究所阴道骶骨固定术及尿失禁减少研究中的学术医疗中心。
患有盆腔器官脱垂且无压力性尿失禁症状的女性。
腹式骶骨阴道固定术,随机分组以决定是否接受Burch阴道悬吊术治疗可能存在的隐匿性尿失禁。
围手术期并发症、盆腔器官脱垂定量评估以及生活质量(QOL)问卷(盆底困扰量表、盆底影响问卷以及医学结局研究简表健康调查(SF-36)),分别于术前、术后即刻、术后6周、3个月及12个月进行调查。
322名年龄在31至82岁之间的女性(21%年龄≥70岁),93%为白人。老年女性基线合并症更多(P<0.001),盆腔器官脱垂更严重(P = 0.003)。在控制脱垂分期及是否进行Burch手术的情况下,并发症发生率无年龄差异。老年女性住院时间更长(3.1±1.0天 vs 2.7±1.5天,P = 0.02),术后6周尿失禁患病率更高(54.7% vs 37.2%,P = 0.005)。在术后3个月和12个月,自我报告的尿失禁、尿失禁压力测试或脱垂分期方面无差异。所有生活质量指标较基线均有显著改善,但无年龄差异。
老年和年轻女性脱垂手术的预后相当,只是老年女性住院时间略长。