Erbek Seyra, Erbek Selim S, Gokmen Zeynel, Ozkiraz Servet, Tarcan Aylin, Ozluoglu Levent N
Department of Otorhinolaryngology, Baskent University, 06640 Bahcelievler, Ankara, Turkey.
Int J Pediatr Otorhinolaryngol. 2007 Aug;71(8):1181-5. doi: 10.1016/j.ijporl.2007.04.007. Epub 2007 May 29.
Auditory and vestibular functions have critical importance in infancy because they may affect motor and mental development. We aimed to determine the normal values of the vestibular evoked myogenic potential (VEMP) parameters to provide a reference for further research regarding the early diagnosis of vestibular dysfunction in newborns.
Twenty-four term newborns (12 girls, 12 boys), with birth weights greater than 2500 g and Apgar scores higher than 7 at 1 min, were studied. Tympanometry, auditory-evoked brainstem responses, transient-evoked otoacoustic emissions, and VEMP recordings were assessed in all subjects during fourth week after birth.
All newborns passed the audiologic evaluation, and biphasic waveforms of the VEMP were obtained in all 48 tested ears. Mean latencies of p13, n23, and p13-n23 intervals were 13.7+/-1.1, 20.5+/-1.6, and 7.1+/-2.1 ms, respectively. The mean amplitude value was 22.6+/-18.4 microV. There were no significant differences in latency values or amplitudes with regard to sex or side of ear tested in newborns.
VEMP may easily be used for early evaluation of vestibular dysfunction in newborns. Because results may differ owing to test techniques and age, every laboratory should have its own normal values.
听觉和前庭功能在婴儿期至关重要,因为它们可能影响运动和智力发育。我们旨在确定前庭诱发肌源性电位(VEMP)参数的正常值,为新生儿前庭功能障碍的早期诊断的进一步研究提供参考。
研究了24名足月儿(12名女孩,12名男孩),出生体重超过2500g,1分钟时阿氏评分高于7分。在出生后第四周对所有受试者进行鼓室图、听觉脑干诱发电位、瞬态诱发耳声发射和VEMP记录评估。
所有新生儿通过听力评估,所有48只受试耳均获得VEMP双相波形。p13、n23和p13-n23间期的平均潜伏期分别为13.7±1.1、20.5±1.6和7.1±2.1ms。平均幅值为22.6±18.4μV。新生儿的潜伏期值或幅值在性别或受试耳侧别方面无显著差异。
VEMP可轻松用于新生儿前庭功能障碍的早期评估。由于结果可能因测试技术和年龄而异,每个实验室应有自己的正常值。