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立体定向脑室腹腔分流术治疗难治性特发性颅内高压

Stereotactic ventriculoperitoneal shunting for refractory idiopathic intracranial hypertension.

作者信息

Abu-Serieh Basel, Ghassempour Keyvan, Duprez Thierry, Raftopoulos Christian

机构信息

Department of Neurosurgery, Saint-Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Neurosurgery. 2007 Jun;60(6):1039-43; discussion 1043-4. doi: 10.1227/01.NEU.0000255456.12978.31.

DOI:10.1227/01.NEU.0000255456.12978.31
PMID:17538377
Abstract

OBJECTIVE

Recent reports have shown promising short- to medium-term results in patients with refractory idiopathic intracranial hypertension (IIH) treated using the stereotactic ventriculoperitoneal shunting (SVPS) technique. However, the long-term clinical efficacy of this technique remains questionable. This report provides the long-term results of SVPS in treating refractory IIH patients.

METHODS

We reviewed the medical charts of nine consecutive patients (mean age, 26.4 yr; range, 4-63 yr) treated using either a frame-based or frameless SVPS technique for IIH.

RESULTS

The mean postoperative follow-up period was 44.3 months (range, 6-110 mo). Before shunting procedures were performed, each patient presented with intractable headache, and five patients (55.6%) had mild to moderate visual deficits. The last follow-up assessment showed that after shunting was performed, eight patients (89%) were headache-free. Only one patient had recurrent headache; however, this patient's pain was much less frequent and severe than before the shunting procedure was completed and was concomitant with recent weight increase. Visual deficits were resolved in three patients and remained stable in two who already had optic nerve atrophy before shunting was completed. Twelve SVPS procedures were performed on our patients. Nine shunt revisions were needed in six patients because of infection (n = 5, including two revisions in one patient), valve dysfunction (n = 2), distal obstruction (n = 1), and ventricular catheter malpositioning (n = 1). No patient had proximal catheter obstruction.

CONCLUSION

Given the favorable long-term outcome of the SVPS technique for refractory IIH, we are encouraged to apply this procedure on our patients. More invasive approaches should be reserved for patients who have SVPS failure.

摘要

目的

近期报告显示,采用立体定向脑室腹腔分流术(SVPS)治疗难治性特发性颅内高压(IIH)患者取得了良好的短期至中期效果。然而,该技术的长期临床疗效仍存在疑问。本报告提供了SVPS治疗难治性IIH患者的长期结果。

方法

我们回顾了连续9例使用基于框架或无框架SVPS技术治疗IIH患者的病历(平均年龄26.4岁;范围4 - 63岁)。

结果

术后平均随访期为44.3个月(范围6 - 110个月)。在进行分流手术前,每位患者均有顽固性头痛,5例患者(55.6%)有轻度至中度视力障碍。最后一次随访评估显示,分流术后8例患者(89%)无头痛。只有1例患者出现复发性头痛;然而,该患者的疼痛频率和严重程度远低于分流手术完成前,且与近期体重增加有关。3例患者的视力障碍得到解决,2例在分流手术前已有视神经萎缩的患者视力保持稳定。我们的患者共进行了12次SVPS手术。6例患者因感染(n = 5,包括1例患者进行了2次翻修)、瓣膜功能障碍(n = 2)、远端梗阻(n = 1)和脑室导管位置异常(n = 1)需要进行9次分流翻修。没有患者出现近端导管梗阻。

结论

鉴于SVPS技术治疗难治性IIH的长期效果良好,我们鼓励对患者应用该手术。对于SVPS失败的患者,应保留更具侵入性的方法。

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