Erdem Fuat, Kiki Ilhami, Gundoğdu Mehmet, Kaya Hasan
Department of Internal Medicine, Division of Hematology, School of Medicine, University of Ataturk, Erzurum, Turkey.
Med Princ Pract. 2007;16(4):324-6. doi: 10.1159/000102159.
To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion.
A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5 degrees C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment.
This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP.
报告一例布鲁氏菌感染并发血栓性血小板减少性紫癜（TTP）的病例，该病例对血浆输注和抗菌治疗反应良好。
一名51岁男性因中度意识模糊、情绪低落和构音障碍入院。他患有慢性病，伴有发热（38.5摄氏度）、贫血、黄疸和瘀点瘀斑性皮肤损害。神经系统检查显示意识减退，格拉斯哥昏迷量表评分为7分，颈部强直为+1级。血红蛋白和血小板计数降低，网织红细胞指数、红细胞沉降率以及血清乳酸脱氢酶升高且存在肾功能不全。TTP为可能的诊断，患者对血浆输注和抗菌治疗反应良好。
本报告表明，针对潜在感染进行治疗并联合血浆输注可能是治疗布鲁氏菌病所致TTP的成功治疗方案。
Zotero 插件